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间歇性普林格尔法与持续性半普林格尔法在腹腔镜下肝Ⅶ段肿瘤切除术中的应用比较

Intermittent Pringle Versus Continuous Half-Pringle Maneuver for Laparoscopic Liver Resections of Tumors in Segment 7.

作者信息

Zhang Yu, Lu Xiangyu, Xu Jian, Yang Hongji, Deng Xiaofan, Chen Kai, Chen Yunfei

机构信息

The Third Department of Hepatobiliary Surgery, Sichuan Academy of Medical Sciences & Sichuan Provincial People's Hospital, School of Medicine, University of Electronic Science and Technology of China, No. 32 West Second Section, First Ring Road, Chengdu, 610072 Sichuan People's Republic of China.

出版信息

Indian J Surg. 2018 Apr;80(2):146-153. doi: 10.1007/s12262-018-1721-8. Epub 2018 Feb 7.

Abstract

Segment 7 is considered an unfavorable portion for laparoscopic hepatectomy because of technical difficulties in exposure and controlling bleeding. We compared intermittent Pringle with continuous half-Pringle maneuver in laparoscopic liver resections of tumors in segment 7. A retrospective analysis was conducted in a total of 36 consecutive patients with tumors in segment 7 undergoing laparoscopic liver resections between July 2011 and February 2016 (16 in the Pringle group versus 20 in the half-Pringle group). The two groups were well matched in baseline characteristics. The operative time (274.5 ± 34.3 versus 237.6 ± 41.8 min), overall declamping time (28.4 ± 8.6 versus 2.3 ± 2.5 min), and ischemic duration (69.7 ± 16.5 versus 52.7 ± 13.2 min) were significantly longer in the Pringle group ( < 0.05). The amount of intraoperative blood loss (612.5 ± 222.3 versus 417.4 ± 163.8 mL) and transfusion (335.2 ± 58.7 versus 224.8 ± 76.2 mL) was significantly greater in the Pringle group ( < 0.05). The Pringle group was associated with significantly lower postoperative albumin and higher C-reactive protein levels on postoperative days 1, 3, and 7 ( < 0.05). Laparoscopic hepatectomy for tumors in segment 7 can be performed safely and effectively with successful exposure of surgical field and proper hepatic blood flow occlusion. Continuous half-Pringle maneuver offers the advantages of less operative time and blood loss, less injury, and better recovery.

摘要

由于暴露和控制出血方面存在技术困难,第7段被认为是腹腔镜肝切除术的不利部位。我们在腹腔镜下对第7段肿瘤进行肝切除时,比较了间断性Pringle法与持续性半Pringle法。对2011年7月至2016年2月期间连续36例接受腹腔镜肝切除的第7段肿瘤患者进行了回顾性分析(Pringle组16例,半Pringle组20例)。两组患者的基线特征匹配良好。Pringle组的手术时间(274.5±34.3对237.6±41.8分钟)、总夹闭时间(28.4±8.6对2.3±2.5分钟)和缺血时间(69.7±16.5对52.7±13.2分钟)明显更长(<0.05)。Pringle组的术中失血量(612.5±222.3对417.4±163.8毫升)和输血量(335.2±58.7对224.8±76.2毫升)明显更多(<0.05)。Pringle组术后第1、3和7天的白蛋白水平明显较低,C反应蛋白水平较高(<0.05)。通过成功暴露手术视野和适当的肝血流阻断,腹腔镜下对第7段肿瘤进行肝切除可以安全有效地进行。持续性半Pringle法具有手术时间和失血量更少、损伤更小、恢复更好的优点。

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