Soliman Youssef Yousry, Soliman Megan Sue, Abbas Farrukh
Internal Medicine Department, Rochester General Hospital, Rochester, New York, USA.
J Community Hosp Intern Med Perspect. 2018 Jun 12;8(3):156-157. doi: 10.1080/20009666.2018.1475189. eCollection 2018.
Drug-induced pancreatitis can be caused by a wide array of medications. In fact, the diagnosis is likely commonly missed due to the difficulty in diagnosing one agent as the sole cause. We present a case of dapsone-induced pancreatitis in a 75-year-old male with history of celiac disease. He presented with abdominal pain and was found to have acute pancreatitis. Interestingly, he had been on dapsone for 5 years and had no other recent medication changes, significant alcohol use, or gallbladder disease. It was determined this was an episode of delayed acute pancreatitis due to dapsone. This is a rarely addressed entity in the literature and is the first case in which pancreatitis occurred so late in a patient's treatment course on dapsone.
药物性胰腺炎可由多种药物引起。事实上，由于难以将某一种药物诊断为唯一病因，该诊断很可能常常被漏诊。我们报告一例75岁患有乳糜泻的男性因氨苯砜诱发胰腺炎的病例。他因腹痛就诊，被诊断为急性胰腺炎。有趣的是，他服用氨苯砜已5年，近期没有其他用药变化、大量饮酒或胆囊疾病史。经判定，这是一例由氨苯砜引起的迟发性急性胰腺炎。这是文献中很少提及的一种情况，也是首例在患者服用氨苯砜治疗过程中这么晚才发生胰腺炎的病例。
