Das Anup K, Jawed Qaiser
Department of Medicine, Assam Medical College, Dibrugarh, Assam, India.
Indian J Pharmacol. 2014 Jul-Aug;46(4):455-7. doi: 10.4103/0253-7613.135967.
Drug-induced acute pancreatitis (AP) is under-reported, and a large number of drugs are listed as offenders, but are often overlooked. Knowledge about the possible association of medications in causing AP is important, and needs a high index of suspicion, especially with drugs that have been reported to be the etiology only rarely. Dapsone, a commonly used drug, can cause various hypersensitivity reactions including AP collectively called "dapsone syndrome." Here, we report dapsone-induced AP in a young man. Our case shows certain dissimilarities like associated acute renal failure and acute hemolysis not previously described.
药物性急性胰腺炎（AP）的报告不足，许多药物被列为致病因素，但往往被忽视。了解药物与AP之间可能的关联很重要，需要高度的怀疑指数，尤其是对于那些仅很少被报道为病因的药物。氨苯砜是一种常用药物，可引起各种超敏反应，包括统称为“氨苯砜综合征”的AP。在此，我们报告一名年轻男性发生的氨苯砜诱导的AP。我们的病例显示出一些不同之处，如伴有急性肾衰竭和急性溶血，这些情况以前未曾描述过。
