Aghajanzadeh Manouchehr, Asgary Mohammad Reza, Mohammadi Fereshteh, Darvishi Haniye, Safarpour Yasaman
Inflammatory Lung Disease Research Center, School of Medicine, Razi Hospital, Guilan University of Medical Science, Rasht, Iran.
J Family Med Prim Care. 2018 Jan-Feb;7(1):224-229. doi: 10.4103/jfmpc.jfmpc_286_17.
Retrosternal goiter refers to any thyroid enlargement in which over 50% of the thyroid permanently located under the thoracic inlet or the lower pole of thyroid is not palpable with the neck in hyperextended position. Due to the increasing number of surgical procedures of retrosternal goiter, the present study was carried out to examine the symptoms, diagnosis, treatment, and treatment complications in retrosternal goiter patients.
Data related to demographic data (age and gender), clinical symptoms (dyspnea, dysphagia, dysphonia, lumps in neck, and hoarseness), methods of diagnosis (computed tomography [CT], chest X-ray [CXR], ultrasonography, and magnetic resonance imaging), and postoperative complications (bleeding, early and late dysphonia, early and late dyspnea, transient and permanent hypocalcemia, transient, and permanent recurrent laryngeal nerve paralysis) were collected.
According to the results 71.4% of patients were women and most of the participants (67.1%) aged 45-60 years. Mass in the neck was the most frequent symptoms before surgery (88.6%). The most common incision for thyroidectomy (95/7%) was neck Collar incision. Diagnosis method in 82.9% and 17.1% of cases was, respectively, based on CT scans with CXR and CT scans with CXR and ultrasound. According to the postoperative pathologic findings, 58.5% of the cases were multinodular goiter, 22.9% were papillary cell carcinoma, 7.1% were medullary carcinoma, 5.7% were anaplastic carcinoma, 5.7% were thyroid lymphoma, and only 1.4% were thyroid adenoma. Postoperative complications occurred in 47.14% of patients. Most common complication was early transient dysphonia.
This study recommends that retrosternal goiter should be operated early under suitable conditions, and the best diagnosis tool and best surgery methods are CT scan and surgery with collar incision, respectively.
胸骨后甲状腺肿是指在颈部过度伸展时,超过50%的甲状腺永久性位于胸廓入口下方或甲状腺下极无法触及的任何甲状腺肿大。由于胸骨后甲状腺肿手术数量的增加,本研究旨在检查胸骨后甲状腺肿患者的症状、诊断、治疗及治疗并发症。
收集与人口统计学数据(年龄和性别)、临床症状(呼吸困难、吞咽困难、声音嘶哑、颈部肿块和声音嘶哑)、诊断方法(计算机断层扫描[CT]、胸部X线[CXR]、超声检查和磁共振成像)以及术后并发症(出血、早期和晚期声音嘶哑、早期和晚期呼吸困难、短暂性和永久性低钙血症、短暂性和永久性喉返神经麻痹)相关的数据。
根据结果,71.4%的患者为女性,大多数参与者(67.1%)年龄在45至60岁之间。颈部肿块是手术前最常见的症状(88.6%)。甲状腺切除术最常见的切口(95/7%)是颈部领式切口。82.9%和17.1%的病例诊断方法分别基于CT扫描结合CXR以及CT扫描结合CXR和超声。根据术后病理结果,58.5%的病例为多结节性甲状腺肿,22.9%为乳头状细胞癌,7.1%为髓样癌,5.7%为未分化癌,5.7%为甲状腺淋巴瘤,只有1.4%为甲状腺腺瘤。47.14%的患者发生术后并发症。最常见的并发症是早期短暂性声音嘶哑。
本研究建议胸骨后甲状腺肿应在合适条件下尽早手术,最佳诊断工具和最佳手术方法分别是CT扫描和领式切口手术。