Elliott Sarah A, Alvarado Alejandro Sánchez
Biotechnology Buzz, Kansas City, MO, USA.
Stowers Insitute for Medical Research, Howard Hughes Medical Institute, Kansas City, MO, USA.
Methods Mol Biol. 2018;1774:207-239. doi: 10.1007/978-1-4939-7802-1_4.
Regeneration has captured human imagination for much of recorded history. Its sociological influence is evident in ancient and modern folklore, art, politics, and even language. In many ways, the study of regeneration helped establish the field of biology as a legitimate scientific discipline. Furthermore, regeneration research yielded critical insights that challenged flawed scientific models and uncovered fundamental principles underpinning the workings of life on this planet. This chapter details some ways in which the study of animal regeneration-with special emphasis on planarian regeneration-influenced the evolution of thought in biology. This includes contributions to the discovery of stem cells, the nature of heredity, and key concepts in pattern formation.
在大部分有记载的历史中，再生现象一直激发着人类的想象力。其社会学影响在古今的民俗、艺术、政治乃至语言中都显而易见。在许多方面，对再生的研究助力生物学领域成为一门正统的科学学科。此外，再生研究带来了至关重要的见解，这些见解挑战了有缺陷的科学模型，并揭示了支撑地球上生命运作的基本原理。本章详细阐述了动物再生研究——特别着重于涡虫再生——影响生物学思想演变的一些方式。这包括对干细胞的发现、遗传的本质以及模式形成中的关键概念所做的贡献。
