Guan R, Oon C J, Wong P K, Foong W C, Wee A
Postgrad Med J. 1985 Apr;61(714):357-9. doi: 10.1136/pgmj.61.714.357.
A 27 year old woman with hepato-lenticular degeneration (Wilson's disease) was found to have primary hepatocellular carcinoma (PHC) three and a half years after she was started on treatment with D-penicillamine. The tumour was resected since when she has remained well. Her liver function tests were normal throughout the course of her disease. The available literature is reviewed and possible mechanisms for this association proposed.
一名27岁的肝豆状核变性（威尔逊病）女性患者，在开始使用D-青霉胺治疗三年半后被发现患有原发性肝细胞癌（PHC）。肿瘤被切除，此后她一直状况良好。在她整个病程中，肝功能检查均正常。本文回顾了现有文献并提出了这种关联的可能机制。
