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年龄相关性干眼与乳铁蛋白和乳糖酸

Age-Related Dry Eye Lactoferrin and Lactobionic Acid.

作者信息

Rusciano Dario, Pezzino Salvatore, Olivieri Melania, Cristaldi Martina, Gagliano Caterina, Lupo Gabriella, Anfuso Carmelina Daniela

机构信息

Sooft Italia SpA, Catania, Italy.

Department of Ophthalmology, University Policlinic, Catania, Italy.

出版信息

Ophthalmic Res. 2018;60(2):94-99. doi: 10.1159/000489093. Epub 2018 Jun 19.

DOI:10.1159/000489093
PMID:29920480
Abstract

Dry eye is the most prominent pathology among those involving the ocular surface: a decrease of the aqueous (less frequent) or the lipid (more frequent) component of the tear film is the cause of the diminished stability of tears that is observed in this pathology. Dry eye shows a clear distribution linked to both sex (being more frequent among women) and age (increasing with aging). Therefore, specific treatments taking into account the etiology of the disease would be desired. The role of lactoferrin and its functional mimetic lactobionic acid are reported here as a possible remedy for age-related dry eye.

摘要

干眼症是累及眼表的最常见病症

泪膜中水液成分(较少见)或脂质成分(较常见)减少,是该病症中观察到的泪液稳定性降低的原因。干眼症在性别(女性中更常见)和年龄(随年龄增长而增加)方面呈现出明显的分布规律。因此,需要考虑疾病病因的特定治疗方法。本文报道了乳铁蛋白及其功能模拟物乳糖酸作为与年龄相关的干眼症的一种可能治疗方法的作用。

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