Favreau J J
Rev Fr Gynecol Obstet. 1985 May;80(6):383-8.
Vulvar carcinoma is relatively rare but genital warts (condylomas) are very frequent findings. Very old diseases, the roles of certain viruses in their pathophysiology has been shown. The mechanism of viral infestation is reviewed. Absolute proof of precise viral oncogenic roles in humans remains unrealized despite definite clinical and epidemiologic arguments; the role is that of a cocarcinogen acting in conjunction with physical, chemical, clinical and immunological factors in an as yet obscure chronological order. For the moment, viral vulvar lesions must be considered as cancer risks and be treated as such.
外阴癌相对罕见，但尖锐湿疣（condylomas）却很常见。这些疾病历史悠久，某些病毒在其病理生理学中的作用已得到证实。本文综述了病毒感染的机制。尽管有明确的临床和流行病学依据，但人类中病毒的确切致癌作用仍未得到确凿证实；其作用是作为一种辅助致癌物，与物理、化学、临床和免疫因素一起，以一种尚不清楚的时间顺序共同起作用。目前，病毒性外阴病变必须被视为癌症风险并据此进行治疗。
