Department of Chemistry, Alzahra University, Vanak, Tehran, Iran.
Chem Rec. 2018 Nov;18(11):1633-1657. doi: 10.1002/tcr.201800022. Epub 2018 Jun 19.
Due to its high potential for the formation of carbon-carbon bonds, Michael addition reaction is one of the closest reactions to the heart of synthetic organic chemists. Electrochemistry presents a very stimulating and divergent resource for selective oxidation and reduction in organic chemistry, generating activated species, for example radical anions or radical cations. In this review, we try to underscore usefulness of electrogenerated Michael addition reaction with the hope of encouraging synthetic organic chemists to contemplate it, as an efficient and green strategy when it is required in their designed multi-step reaction pathways.
由于迈克尔加成反应具有形成碳-碳键的高潜力，因此它是最接近合成有机化学家核心的反应之一。电化学在有机化学中为选择性氧化和还原提供了非常刺激和多样化的资源，生成活化物种，例如自由基阴离子或自由基阳离子。在这篇综述中，我们试图强调电生迈克尔加成反应的有用性，希望鼓励合成有机化学家在需要时将其视为一种有效且绿色的策略，纳入他们设计的多步反应途径中。
