From the Department of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh; Cincinnati Children's Hospital Medical Center, Cincinnati; the Department of Psychiatry, University of Cincinnati College of Medicine, Cincinnati; the Western Psychiatric Institute and Clinic, University of Pittsburgh Medical Center, Pittsburgh; and the Department of Statistics, University of Pittsburgh, Pittsburgh.
Am J Psychiatry. 2018 Sep 1;175(9):887-896. doi: 10.1176/appi.ajp.2018.17070792. Epub 2018 Jun 20.
The authors sought to determine the long-term impact of sudden parental death on youths and pathways between youth bereavement and impairment.
Youths (N=216) who lost a parent to suicide, accident, or sudden natural death and nonbereaved youths (N=172) were followed periodically for up to 7 years. The incidence and prevalence of disorder and of functional impairment, as well as pathways to impairment, were assessed using Cox and mixed-effects logistic regression and structural equation modeling.
Prior to parental death, bereaved youths had higher rates of psychiatric disorder, parental psychiatric disorder, and maltreatment. Even after adjustment for predeath risk factors, bereavement was associated with an increased incidence of depression, posttraumatic stress disorder, and functional impairment. The peak incidence of depression was in the first 2 years postbereavement, with incident depression occurring mainly in those who lost a parent at age 12 or younger. Youths bereaved by all three causes of death showed higher rates of impairment at all time points. Structural equation modeling found that bereavement had a direct effect on impairment and was also linked to impairment via its effects on early and later depression and through negative life events. Child psychiatric disorder prior to parental loss also contributed to functional impairment.
Parental death increased the incidence of depression in offspring early in the course of bereavement. Early identification and treatment of depression in bereaved youths and augmentation of family resilience may protect against later sequelae of functional impairment.
作者旨在探讨父母突然离世对青少年的长期影响以及青少年丧亲与功能障碍之间的关系途径。
对 216 名因自杀、意外或突发自然死亡而失去父母的青少年(丧亲组)和 172 名非丧亲青少年(对照组)进行了长达 7 年的定期随访。采用 Cox 和混合效应逻辑回归以及结构方程模型评估了障碍和功能障碍的发生率和患病率,以及导致功能障碍的途径。
在父母去世之前,丧亲的青少年有更高的精神障碍、父母精神障碍和受虐待的发生率。即使在调整了死亡前的风险因素后,丧亲仍与抑郁、创伤后应激障碍和功能障碍的发生率增加相关。抑郁的发病高峰出现在丧亲后的前 2 年,丧亲后发生抑郁的主要是在 12 岁或更小年龄失去父母的人。因三种死因而丧亲的青少年在所有时间点的功能障碍发生率都更高。结构方程模型发现丧亲对功能障碍有直接影响,并且还通过对早期和晚期抑郁的影响以及通过负面生活事件与功能障碍相关。丧亲前儿童精神障碍也导致了功能障碍。
父母的去世增加了丧亲青少年在丧亲过程早期抑郁的发生率。早期识别和治疗丧亲青少年的抑郁,增强家庭的适应能力,可能有助于预防以后出现功能障碍的后果。