Pötzi P, Huber J, Kühböck J, Weber H
Acta Med Austriaca Suppl. 1979;6:339-41.
185 electrocardiograms, of a total of 39 patients were analyzed during and after Adriamycin treatment. Total Adriamycin doses did not exceed 70--120 mg in each course, respecting the 550 mg/m2 limit. ECG changes were found in 80% of such therapeutic regimen, changes of heart-rate, PQ, QT-intervals and ST/T predominating, Arrhythmias (supraventricular and ventricular ectopic beats as well as AV-blocks grade I--II) were observed in several patients.
在阿霉素治疗期间及之后,对总共39例患者的185份心电图进行了分析。每个疗程阿霉素的总剂量不超过70 - 120毫克,遵循550毫克/平方米的限制。在80%的此类治疗方案中发现了心电图变化,主要是心率、PQ、QT间期和ST/T的变化,在数名患者中观察到心律失常(室上性和室性异位搏动以及I - II度房室传导阻滞)。