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恶性胸肺小细胞(“阿斯金”)肿瘤。

Malignant thoracopulmonary small-cell ("Askin") tumor.

作者信息

Fink I J, Kurtz D W, Cazenave L, Lieber M R, Miser J S, Chandra R, Triche T J

出版信息

AJR Am J Roentgenol. 1985 Sep;145(3):517-20. doi: 10.2214/ajr.145.3.517.

DOI:10.2214/ajr.145.3.517
PMID:2992255
Abstract

The clinical, radiographic, and pathologic features of 10 patients with documented malignant small-cell tumor of the thoracopulmonary region (Askin tumor) were reviewed. The tumor represents a distinct pathologic entity of neuroectodermal origin. Clinically, it presents as a chest-wall mass with or without pain. Its radiographic appearance is that of a soft-tissue mass with or without pleural or rib involvement, often with metastatic disease--to the skeletal system, bone marrow, thorax, and sympathetic chain. Two patients developed metastases to the adrenal gland and liver, one after autologous bone marrow transplantation. The radiologist should be aware of this entity and its pattern of metastatic spread since metastases are treated aggressively.

摘要

回顾了10例有记录的胸肺区域恶性小细胞肿瘤(阿斯金瘤)患者的临床、影像学和病理特征。该肿瘤代表一种独特的神经外胚层起源的病理实体。临床上,它表现为有或无疼痛的胸壁肿块。其影像学表现为有或无胸膜或肋骨受累的软组织肿块,常伴有转移至骨骼系统、骨髓、胸部和交感神经链。两名患者发生肾上腺和肝脏转移,其中一名是在自体骨髓移植后。放射科医生应了解这种实体及其转移扩散模式,因为对转移灶需积极治疗。

相似文献

1
Malignant thoracopulmonary small-cell ("Askin") tumor.恶性胸肺小细胞(“阿斯金”)肿瘤。
AJR Am J Roentgenol. 1985 Sep;145(3):517-20. doi: 10.2214/ajr.145.3.517.
2
Primitive neuroectodermal tumors of the chest wall (Askin tumors): CT and MR findings.胸壁原始神经外胚层肿瘤(阿斯金瘤):CT与MR表现
AJR Am J Roentgenol. 1993 Aug;161(2):265-8. doi: 10.2214/ajr.161.2.8392786.
3
Synchronous presentation of an Askin tumor and a plasmacytoma in an adult patient.一名成年患者同时出现Askin肿瘤和浆细胞瘤。
Tumori. 2003 May-Jun;89(3):324-7. doi: 10.1177/030089160308900318.
4
[Peripheral neuroectodermal tumors of the chest wall. Description of a case].[胸壁周围神经外胚层肿瘤。病例描述]
Minerva Chir. 1998 Apr;53(4):299-303.
5
Does malignant small round cell tumor of the thoracopulmonary region (Askin tumor) constitute a clinicopathologic entity? An analysis of 30 cases with immunohistochemical and electron-microscopic support treated at the Institute Gustave Roussy.胸肺区域恶性小圆细胞瘤(阿斯金瘤)是否构成一种临床病理实体?对古斯塔夫·鲁西研究所治疗的30例病例进行的免疫组化和电子显微镜分析。
Cancer. 1992 Feb 15;69(4):1012-20. doi: 10.1002/1097-0142(19920215)69:4<1012::aid-cncr2820690431>3.0.co;2-v.
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Malignant small-cell tumor of the thoracopulmonary region: 'Askin tumor'.胸肺区域恶性小细胞肿瘤:“阿斯金瘤”
J Pediatr Surg. 1989 Oct;24(10):1079-83. doi: 10.1016/s0022-3468(89)80221-0.
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Fine needle aspiration cytologic findings in malignant small cell tumor of the thoracopulmonary region (Askin tumor).
Acta Cytol. 1994 Sep-Oct;38(5):702-6.
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Newly established Askin tumor cell line and overexpression of focal adhesion kinase in Ewing sarcoma family of tumors cell lines.
Cancer Genet Cytogenet. 2003 Oct 15;146(2):102-9. doi: 10.1016/s0165-4608(03)00129-8.
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[Askin tumor. Consideration on a case].[Askin瘤。关于一例病例的思考]
Pneumologia. 2006 Jan-Mar;55(1):32-5.
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[Askin tumor: two cases].[Askin瘤:两例报告]
Rev Pneumol Clin. 2002 Dec;58(6 Pt 1):347-50.

引用本文的文献

1
Askin tumor: CT and FDG-PET/CT imaging findings and follow-up.Askin肿瘤:CT及FDG-PET/CT影像学表现及随访
Medicine (Baltimore). 2014 Jul;93(6):e42. doi: 10.1097/MD.0000000000000042.
2
Askin tumor with metastasis to the scalp: a histochemical, immunohistochemical and ultrastructural study.伴有头皮转移的Askin肿瘤:一项组织化学、免疫组织化学及超微结构研究。
Med Mol Morphol. 2006 Dec;39(4):221-5. doi: 10.1007/s00795-006-0333-8. Epub 2006 Dec 21.
3
Askin tumor: a malignant small cell tumor.Askin肿瘤:一种恶性小细胞肿瘤。
Indian J Pediatr. 2000 Nov;67(11):853-5. doi: 10.1007/BF02726235.
4
Mass on chest X-ray.胸部X光片上有肿物。
Postgrad Med J. 1997 Aug;73(862):515-7. doi: 10.1136/pgmj.73.862.515.
5
Malignant peripheral neuroectodermal tumors in urology.泌尿外科中的恶性外周神经外胚层肿瘤
World J Urol. 1995;13(4):226-9. doi: 10.1007/BF00182967.
6
Clinical and radiologic analysis of 13 cases of primary neuroectodermal tumors of bone.13例骨原发性神经外胚层肿瘤的临床与影像学分析
Skeletal Radiol. 1989;18(2):115-20. doi: 10.1007/BF00350659.