Khan Aleena Ahmad, Perveen Rukhsana, Sheikh Nadeem, Abbasi Babar Hilal Ahmad, Batool Zunaira, Shahzad Muhammad, Kaleem Sana
Forensic Services Laboratory, Centre for Applied Molecular Biology, University of the Punjab, Lahore, Pakistan.
Centre for Advanced Studies in Vaccinology and Biotechnology, University of Balochistan, Quetta, Pakistan.
Int J Legal Med. 2019 May;133(3):775-776. doi: 10.1007/s00414-018-1878-5. Epub 2018 Jun 20.
Allele frequencies and forensic statistical parameters of 15 autosomal short tandem repeats (STRs) were evaluated in 200 genetically unrelated individuals of the Baloch population of Pakistan. Total 155 alleles were observed with allele frequencies ranged from 0.003 to 0.425. Among the 15 STRs, D2S1338 was found to be the most polymorphic and discriminating locus while TPOX was the least polymorphic and discriminating locus. The combined power of discrimination (CPD), combined power of exclusion (CPE), and combined matching probability (CMP) were found to be 0.9999999999999999978, 0.999994252, and 2.14012 × 10, respectively. No significant deviation from Hardy-Weinberg Equilibrium (HWE) was observed except for locus D21S11. Additionally, a correlation between previously published data and Baloch population is also presented.
在200名巴基斯坦俾路支人群体中无亲缘关系的个体中，评估了15个常染色体短串联重复序列（STR）的等位基因频率和法医统计参数。共观察到155个等位基因，其频率范围为0.003至0.425。在这15个STR中，D2S1338被发现是多态性和鉴别力最高的位点，而TPOX是多态性和鉴别力最低的位点。鉴别力联合概率（CPD）、排除联合概率（CPE）和匹配联合概率（CMP）分别为0.9999999999999999978、0.999994252和2.14012×10。除了D21S11位点外，未观察到与哈迪-温伯格平衡（HWE）的显著偏差。此外，还呈现了先前发表的数据与俾路支人群体之间的相关性。
