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中国维吾尔族人群21个常染色体STR基因座的遗传多态性

Genetic polymorphisms of 21 autosomal STR loci in Chinese Uygur ethnic population.

作者信息

Song Xingbo, Gou Haimei, Zhong Huiyu, Zhang Zhaoxia, Wang Liang, Wang Minjin, Zhou Juan, Zhou Yi, Lu Xiaojun, Wang Jun, Ying Binwu

机构信息

Department of Laboratory Medicine, West China Hospital, Sichuan University, Chengdu, Sichuan Province, 610041, People's Republic of China.

Department of Clinical Laboratory, First Affiliated Hospital of Xinjiang Medical University, Urumqi, Xinjiang Province, 830054, People's Republic of China.

出版信息

Int J Legal Med. 2018 Nov;132(6):1637-1639. doi: 10.1007/s00414-018-1913-6. Epub 2018 Aug 20.

DOI:10.1007/s00414-018-1913-6
PMID:30128636
Abstract

Genetic polymorphisms of 21 short tandem repeat (STR) loci were studied in 576 unrelated Uygur individuals living in Urumqi using Goldeneye™ DNA ID 22NC system. Population data of all loci, except one locus (D1S1656), had no significant deviation from Hardy-Weinberg equilibrium. A high degree of genetic polymorphisms was showed by all STR loci in Urumchi Uygur population. The combined power of discrimination (CPD) was 0.999999999999999999999999985256 and the combined power of exclusion (CPE) was 0.999999997207836. In addition, we performed comparisons between the data from Uygur population with previously published data obtained from other populations.

摘要

利用Goldeneye™ DNA ID 22NC系统,对居住在乌鲁木齐的576名无血缘关系的维吾尔族个体的21个短串联重复序列(STR)位点的基因多态性进行了研究。除一个位点(D1S1656)外,所有位点的群体数据均未显著偏离哈迪-温伯格平衡。乌鲁木齐维吾尔族群体中的所有STR位点均表现出高度的基因多态性。鉴别力联合概率(CPD)为0.999999999999999999999999985256,排除力联合概率(CPE)为0.999999997207836。此外,我们将维吾尔族群体的数据与先前发表的其他群体的数据进行了比较。

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本文引用的文献

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