Gu Zhengfeng, Xin Lian, Wang Zhiping, Wang Jun
Department of Anesthesiology, People's Hospital of Wuxi, Jiangsu, China.
Medicine (Baltimore). 2018 Jun;97(25):e11108. doi: 10.1097/MD.0000000000011108.
Congenital heart disease and pulmonary arterial hypertension are perilous to a gravida for the high morbidity and mortality.
We report an extremely rare case of a 27-year-old gravida with congenital heart disease and severe pulmonary arterial hypertension of 115 mmHg. Arterial blood gas analysis revealed her oxygen saturation (SpO2) of 67.8% and oxygen partial pressure of 40.0 mmHg, which were severely low. The patient was diagnosed as having gestation combined with congenital heart disease, severe pulmonary arterial hypertension, and hypoxemia.
The patient was treated with surgical abortion. The patient was monitored with invasive blood pressure (BP), electrocardiogram (ECG), heart rate, SpO2, and arterial gas analysis as from entry into the operation suite. We performed total intravenous anesthesia with nitroglycerin inhalation. She was returned to the ward at the end of surgery.
To our knowledge, this is the first reported case in a gravida with severe heart disease and very low SpO2. Nitroglycerin inhalation may provide dilation of the pulmonary artery, reduction of pulmonary artery pressure, and improvement of oxygenation. Our case report may provide alternative regimen to anesthesia practitioners in similar circumstances.
先天性心脏病和肺动脉高压对孕妇来说具有很高的发病率和死亡率,十分危险。
我们报告一例极其罕见的病例,一名27岁孕妇患有先天性心脏病,肺动脉高压严重,达115毫米汞柱。动脉血气分析显示其氧饱和度(SpO2)为67.8%,氧分压为40.0毫米汞柱,严重偏低。该患者被诊断为妊娠合并先天性心脏病、严重肺动脉高压和低氧血症。
对该患者实施了手术流产。自进入手术室起,对患者进行有创血压(BP)、心电图(ECG)、心率、SpO2和动脉血气分析监测。我们采用静脉全身麻醉并吸入硝酸甘油。手术结束后患者返回病房。
据我们所知,这是首例报道的患有严重心脏病且SpO2极低的孕妇病例。吸入硝酸甘油可能会使肺动脉扩张,降低肺动脉压力,并改善氧合。我们的病例报告可为麻醉医生在类似情况下提供替代方案。