Cruz Natasha Ferreira Santos da, Brandão Larissa Silva, Cruz Sérgio Ferreira Santos da, Cruz Sérgio Augusto Sequeira da, Pires Carla Andréa Avelar, Carneiro Francisca Regina Oliveira
Ophthalomology Department, Irmandade da Santa Casa de Misericórdia de São Paulo, São Paulo, SP, Brazil.
Pediatric Department, Instituto de Assistência Médica ao Servidor Público Estadual, São Paulo, SP, Brazil.
Arq Bras Oftalmol. 2018 Jun;81(3):219-225. doi: 10.5935/0004-2749.20180044.
We aimed to report the ocular manifestations observed in patients with psoriasis.
Patients were included and referred to our ophthalmology clinic from dermatology clinics of Universidade do Estado do Pará between October 2013 and August 2014. Clinical interviews were conducted to identify relevant epidemiological data, clinical features, and treatment details, and data were recorded using the same protocol. Subsequent dermatological examinations were performed and disease severity was rated using the Psoriasis Area and Severity Index and the Dermatological Life Quality Index. Complete eye examination was conducted, including visual acuity, biomicroscopy, tonometry, fundoscopy, Schirmer I test, tear breakup time, rose bengal staining, ocular surface disease index, and glaucoma tests.
In total, we included 43 patients with psoriasis and 86 controls. Patients with psoriasis had statistically higher incidences of dry eye (16.28%), likely dry eye (32.56%), and blepharitis (16.28%). Furthermore, the rose bengal and ocular surface disease tests were more abnormal in patients with psoriasis (p<0.05).
Patients with psoriasis should undergo regular eye exams, regardless of risk factors, to monitor for the progression of symptomatic or asymptomatic ocular manifestations.
我们旨在报告银屑病患者中观察到的眼部表现。
2013年10月至2014年8月期间，患者从帕拉州立大学皮肤科诊所被纳入并转诊至我们的眼科诊所。进行临床访谈以确定相关的流行病学数据、临床特征和治疗细节，并使用相同的方案记录数据。随后进行皮肤科检查，并使用银屑病面积和严重程度指数以及皮肤病生活质量指数对疾病严重程度进行评级。进行全面的眼部检查，包括视力、生物显微镜检查、眼压测量、眼底镜检查、Schirmer I试验、泪膜破裂时间、孟加拉玫瑰红染色、眼表疾病指数和青光眼检查。
我们总共纳入了43例银屑病患者和86例对照。银屑病患者干眼症（16.28%）、可能的干眼症（32.56%）和睑缘炎（16.28%）的发生率在统计学上更高。此外，银屑病患者的孟加拉玫瑰红和眼表疾病检查结果更异常（p<0.05）。
银屑病患者无论有无危险因素，都应定期进行眼部检查，以监测有症状或无症状眼部表现的进展情况。
