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埃及银屑病患者样本中眼部检查结果的患病率

Prevalence of ocular findings in a sample of Egyptian patients with psoriasis.

作者信息

Omar Salma Samir, Helaly Hany Ahmed

机构信息

Department of Dermatology, Venereology and Andrology, Faculty of Medicine, Alexandria University, Alexandria, Egypt.

Department of Ophthalmology, Faculty of Medicine, Alexandria University, Alexandria, Egypt.

出版信息

Indian J Dermatol Venereol Leprol. 2018 Jan-Feb;84(1):34-38. doi: 10.4103/ijdvl.IJDVL_1239_15.

Abstract

BACKGROUND

Psoriasis is a common disorder worldwide. The prevalence of psoriasis in Egypt, an African country with a Caucasian population, ranges 0.19-3%. Despite this relatively high prevalence of psoriasis, there are no epidemiologic data regarding the burden of associated eye affection. Determining the magnitude of the problem could help in offering better integrated health services.

AIM

The purpose of this study was to evaluate eye involvement in a sample of Egyptian psoriatic patients.

PATIENTS AND METHODS

This case-control study included 100 patients with psoriasis and 100 age and sex matched healthy controls. Psoriasis extent and severity was graded by psoriasis area and severity index (PASI). Complete ophthalmological examination and tests for dry eye were performed to all subjects.

RESULTS

The mean age of the psoriasis group was 50.7 ± 14.3 years. Thirty eight percent of the cases were females. The mean duration of psoriasis was 10.1 ± 7.5 years. Psoriasis patients had more conjunctival injection (n = 40, P = 0.035), more pinguecula (n = 38, P = 0.048) than controls. Ocular surface disease index (OSDI), tear breakup time (TBUT), Schirmer I, and Rose Bengal staining showed statistically significant positive results in the psoriasis group.

CONCLUSION

This is the first report on the prevalence of eye comorbidities in Egyptian psoriatic patients. Dry eyes were more common with psoriasis, particularly the erythrodermic type. Other ocular findings were not statistically significantly different except for conjunctival injection and pinguecula.

摘要

背景

银屑病是一种全球常见的疾病。在埃及这个拥有高加索人种的非洲国家,银屑病的患病率在0.19%至3%之间。尽管银屑病的患病率相对较高,但尚无关于相关眼部病变负担的流行病学数据。确定该问题的严重程度有助于提供更好的综合医疗服务。

目的

本研究旨在评估埃及银屑病患者样本中的眼部受累情况。

患者与方法

本病例对照研究纳入了100例银屑病患者和100例年龄及性别匹配的健康对照。银屑病的范围和严重程度通过银屑病面积和严重程度指数(PASI)进行分级。对所有受试者进行了全面的眼科检查和干眼测试。

结果

银屑病组的平均年龄为50.7±14.3岁。38%的病例为女性。银屑病的平均病程为10.1±7.5年。银屑病患者的结膜充血(n = 40,P = 0.035)、睑裂斑(n = 38,P = 0.048)比对照组更多。眼表疾病指数(OSDI)、泪膜破裂时间(TBUT)、Schirmer I试验和孟加拉玫瑰红染色在银屑病组显示出具有统计学意义的阳性结果。

结论

这是关于埃及银屑病患者眼部合并症患病率的首份报告。干眼在银屑病患者中更为常见,尤其是红皮病型。除结膜充血和睑裂斑外,其他眼部表现无统计学显著差异。

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