Macalupú Susana Zurita
Laboratorio de Referencia Nacional de Micología, Instituto Nacional de Salud. Lima, Perú.
Rev Peru Med Exp Salud Publica. 2018 Jan-Mar;35(1):126-131. doi: 10.17843/rpmesp.2018.351.3563.
We are currently witnessing a constant and ongoing change of the epidemiological pictures of yeast resistance to antifungal agents, related to the type of host, etiology of the disease, the microorganism involved, and its mechanisms of resistance. This epidemiological situation complicates management of patients with infections of the bloodstream due to species of the genus Candida, exhibiting a high mortality and an increase in the use of anti-fungal agents, as well as the need to develop reliable methods to conduct sensitivity studies. Therefore, local and regional monitoring is important in order to know the sensitivity profile and the distribution of Candida species so as to start an adequate anti-fungal therapy.
目前，我们正目睹酵母菌对抗真菌药物的耐药性流行病学情况不断持续变化，这与宿主类型、疾病病因、所涉及的微生物及其耐药机制有关。这种流行病学情况使念珠菌属物种引起的血流感染患者的管理变得复杂，此类感染死亡率高，抗真菌药物的使用增加，并且需要开发可靠的方法来进行敏感性研究。因此，为了了解念珠菌属物种的敏感性概况和分布情况以便开始适当的抗真菌治疗，进行局部和区域监测很重要。
