Academic Unit of Health and Wellness, Faculty of Dentistry, Catholic University of Cuenca, Cuenca 010105, Ecuador.
Research Group: Innovation and Pharmaceutical Development in Dentistry Research Group, Faculty of Dentistry, Head of Research and Innovation, Catholic University of Cuenca, Cuenca 010105, Ecuador.
Biomolecules. 2022 Jun 4;12(6):789. doi: 10.3390/biom12060789.
The pathologies produced by fungi in the oral cavity in recent decades have become a health problem, with factors such as an imbalance of the local microbiota being the cause for their propagation. Conventional antifungal treatments, instead of being beneficial, have generated alterations that have led to antifungal resistance. The aim of this study was to investigate and describe phytotherapy resources as a possible solution to oral antifungal resistance. A bibliographic search was carried out on platforms such as PubMed, Scopus, ScienceDirect, Web of Science, and Google scholar. A total of 248 scientific articles were obtained, of which 108 met the inclusion criteria. Microorganisms of fungal origin currently show resistance to the different antifungals of conventional use, which is undoubtedly altering the oral health of human beings, but there are new therapeutic possibilities such as the active principles of various natural species.
近几十年来，真菌在口腔中引起的疾病已成为一个健康问题，局部微生物群落失衡等因素是其传播的原因。传统的抗真菌治疗方法不仅没有带来益处，反而产生了导致抗真菌耐药性的变化。本研究旨在调查和描述植物疗法资源，作为解决口腔抗真菌耐药性的一种可能方法。在 PubMed、Scopus、ScienceDirect、Web of Science 和 Google Scholar 等平台上进行了文献检索，共获得 248 篇科学文章，其中 108 篇符合纳入标准。目前，真菌来源的微生物对常规使用的不同抗真菌药物表现出耐药性，这无疑正在改变人类的口腔健康，但也有新的治疗可能性，如各种天然物种的活性成分。
