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[砷的摄入:对人类营养与健康的影响]

[Arsenic Intake: Impact in Human Nutrition and Health].

作者信息

Medina-Pizzali María, Robles Pamela, Mendoza Mónica, Torres Celeste

机构信息

Facultad de Ciencias de la Salud, Universidad Peruana de Ciencias Aplicadas. Lima, Perú.

Facultad de Ciencias de la Salud, Universidad Científica del Sur. Lima Perú.

出版信息

Rev Peru Med Exp Salud Publica. 2018 Jan-Mar;35(1):93-102. doi: 10.17843/rpmesp.2018.351.3604.

Abstract

Arsenic is an element that is widely distributed throughout the environment. Its compounds are mainly in the state of pentavalent and trivalent oxidation; and in inorganic and organic forms. Arsenical species vary in their degree of toxicity, with inorganic compounds being more toxic than organic and trivalent compounds more toxic than pentavalent compounds. There would be interconversion between the less toxic species and other more toxic species and the cooking and processing methods could affect it. Arsenic is a carcinogenic agent and causes multiple negative effects on human health in the short and long term. Non-occupational human exposure to arsenic occurs mainly through water and food. The regulation is variable for each country and is based on WHO standards, the Codex Alimentarius, and the European Union. Many studies focus on determining the total arsenic content but do not identify arsenical species in foods. Globally, fish and seafood, chicken, meat, rice, and seaweed have high levels of arsenic. In Peru, there are few studies on total arsenic content and arsenical species in food despite the fact that we have areas with high levels of environmental contamination. The objective of this review is to discuss exposure to arsenic through food and water intake, related regulations, toxicity, consequences on human health and main foods that contribute to its intake.

摘要

砷是一种广泛分布于环境中的元素。其化合物主要以五价和三价氧化态存在,且有无机和有机两种形式。砷的种类毒性程度各异,无机化合物比有机化合物毒性更强,三价化合物比五价化合物毒性更强。毒性较低的种类与其他毒性更强的种类之间会发生相互转化,烹饪和加工方法可能会对此产生影响。砷是一种致癌物质,会在短期和长期内对人类健康造成多种负面影响。人类非职业性接触砷主要通过水和食物。各国的相关规定各不相同,其依据是世界卫生组织标准、食品法典以及欧盟标准。许多研究侧重于测定食品中的总砷含量,但并未鉴定其中的砷种类。在全球范围内,鱼类、海鲜、鸡肉、肉类、大米和海藻中的砷含量较高。在秘鲁,尽管我们有环境污染程度较高的地区,但关于食品中总砷含量和砷种类的研究却很少。本综述的目的是讨论通过食物和饮水摄入砷的情况、相关规定、毒性、对人类健康的影响以及导致砷摄入的主要食物。

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