Essiben F, Foumane P, Mboudou E T, Dohbit J S, Mve Koh V, Ndom P
Département de Gynécologie-Obstétrique, Faculté de Médecine et des Sciences Biomédicales, Université de Yaoundé 1, Cameroun.
Service de Gynécologie-Obstétrique, Hôpital Gynéco-Obstétrique et Pédiatrique de Yaoundé, Cameroun.
Mali Med. 2013;28(1):1-5.
The objective was to describe the clinical and therapeutic aspects of breast cancer at the Yaounde Gynaeco-Obstetric and Pediatric Hospital, which is a referral centre for gynecological malignancies.
It was a retrospective descriptive study over a period of four years, from June 1 2003 to May 31 2007.
Sixty five patients were identified during the study period. The mean age and parity were respectively 42.9 ±13.6 years and 3.9 ± 2.1. The mean age of onset of the first menses was 14.0 ± 1.5 years. Most patients were under 50 (72.3%) and had given birth at least once (89.2%). Non menopausal period (75.4%) and breastfeeding (76.9%) were frequently found. The patients consulted 9.2 ± 3.4 months after the onset of symptoms, with 78.5% of cases arriving at a local advanced clinical stage. Ductal carcinoma accounted for 75.4% of histological types, SBR grades 1 and 2 being the most frequent (89.2%). Chemotherapy (69.2% of the cases) and surgery (67.7% of the cases) often radical (three out of four) were the main treatment modalities used.
In Yaounde, breast cancer is often a ductal carcinoma of high histological grade, attacking the quarantine non menopausal woman, who gave birth and breastfed at least once, diagnosed with a local clinical advanced disease. Chemotherapy and surgery are the main therapeutic options implemented.
本研究旨在描述雅温得妇产科和儿科医院（一所妇科恶性肿瘤转诊中心）乳腺癌的临床及治疗情况。
这是一项为期四年的回顾性描述性研究，时间跨度为2003年6月1日至2007年5月31日。
研究期间共确诊65例患者。平均年龄和平均产次分别为42.9±13.6岁和3.9±2.1。初潮的平均年龄为14.0±1.5岁。大多数患者年龄在50岁以下（72.3%）且至少生育过一次（89.2%）。常见处于非绝经期（75.4%）和正在哺乳（76.9%）。患者在出现症状后9.2±3.4个月前来就诊，78.5%的病例就诊时已处于局部晚期临床阶段。导管癌占组织学类型的75.4%，SBR 1级和2级最为常见（89.2%）。主要治疗方式为化疗（69.2%的病例）和手术（67.7%的病例），手术多为根治性（四分之三）。
在雅温得，乳腺癌通常是高组织学分级的导管癌，侵袭对象为处于非绝经期、至少生育过一次且正在哺乳的女性，确诊时多为局部临床晚期疾病。化疗和手术是主要的治疗选择。
