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[Scleromyxedema as a systemic disease of glycosaminoglycan accumulation].

作者信息

Radenska-Lopovok S G, Volkova P, Gorodetsky V R, Egorova O N, Ananyeva L P

机构信息

I.M. Sechenov First Moscow State Medical University, Ministry of Health of Russia, Moscow, Russia; Russian Medical Academy of Continuing Professional Education, Ministry of Health of Russia, Moscow, Russia.

N.I. Pirogov Russian National Research Medical University, Ministry of Health of Russia, Moscow, Russia.

出版信息

Arkh Patol. 2018;80(3):53-58. doi: 10.17116/patol201880353-58.

Abstract

Scleromyxedema is a rare mucinosis with a primary skin lesion due to diffuse mucin deposition, sclerosis, and lichenoid eruptions in the absence of hypothyroidism. The paper describes scleromyxedema cases and gives recommendations for the histological diagnosis of the disease by histochemical reactions to detect acid and neutral glycosaminoglycans.

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