Rorke L B, Gilles F H, Davis R L, Becker L E
Cancer. 1985 Oct 1;56(7 Suppl):1869-86. doi: 10.1002/1097-0142(19851001)56:7+<1869::aid-cncr2820561330>3.0.co;2-0.
A classification for childhood brain tumors based upon revision of nomenclature of all brain tumors published by the World Health Organization (WHO) in 1979 is proposed. Applicability of the WHO classification scheme was tested in a combined study of the clinical and pathologic features of approximately 3300 brain tumors in children. It was found to be adequate for many of the neoplasms but unsuitable for a significant proportion, including a number of complex cerebral tumors for which there was no appropriate name. Nomenclature of poorly differentiated or densely cellular neuroepithelial tumors was simplified to reflect the current state of knowledge of neuroembryology and neuro-oncology, although the Committee members recognized that such a proposal would likely perpetuate the long-standing and continuing controversy relative to the nature and origin of these neoplasms.
本文提出了一种基于对世界卫生组织（WHO）1979年发布的所有脑肿瘤命名法修订的儿童脑肿瘤分类方法。WHO分类方案的适用性在一项对约3300例儿童脑肿瘤的临床和病理特征的联合研究中进行了测试。结果发现，该分类方案对许多肿瘤适用，但对相当一部分肿瘤不适用，包括一些没有合适名称的复杂脑肿瘤。低分化或细胞密集的神经上皮肿瘤的命名被简化，以反映神经胚胎学和神经肿瘤学的当前知识状态，尽管委员会成员认识到这样的提议可能会使关于这些肿瘤的性质和起源的长期争议持续下去。
