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髋臼侵袭性骨母细胞瘤:诊断难题。

Aggressive osteoblastoma of the acetabulum: A diagnostic dilemma.

作者信息

Sharma Abhimanyu, Gogoi Priyanka, Arora Rajesh, Haq Rehan Ul, Dhammi Ish Kumar, Bhatt Shuchi

机构信息

Department of Pathology, University College of Medical Sciences and Guru Teg Bahadur hospital, Dilshad Garden, Delhi, 110095, India.

Department of Orthopaedics, University College of Medical Sciences and Guru Teg Bahadur hospital, Dilshad Garden, Delhi, 110095, India.

出版信息

J Clin Orthop Trauma. 2018 Jun;9(Suppl 2):S21-S25. doi: 10.1016/j.jcot.2017.09.007. Epub 2017 Sep 18.

Abstract

Osteoblastoma is a rare tumor and represents about 0.8% of all bone tumors. The aggressive variant is even rarer and difficult to diagnose. We present a case of a 17 year old male with a tumor of the acetabulum with characteristic epithelioid osteoblasts and other features of an aggressive osteoblastoma. It is important to recognize this entity as it can be clinically confused with an osteosarcoma. Our case not only showed epithelioid morphology but also had vacuolated cytoplasm, which simulated a mucin secreting adenocarcinoma. Since treatment and prognosis for these entities is strikingly different, an accurate diagnosis becomes all the more important. This case emphasizes the need for better co-ordination between the clinician and pathologist and use of histochemical stains and immunohistochemistry apart from routine histopathology for arriving at a final diagnosis. It is essential to have a close follow-up of the patient to look for recurrence of the tumor.

摘要

骨母细胞瘤是一种罕见肿瘤,约占所有骨肿瘤的0.8%。侵袭性变体更为罕见,且难以诊断。我们报告一例17岁男性髋臼肿瘤病例,其具有特征性上皮样成骨细胞及侵袭性骨母细胞瘤的其他特征。认识到这一实体很重要,因为它临床可能与骨肉瘤混淆。我们的病例不仅显示上皮样形态,还具有空泡状细胞质,类似分泌黏液的腺癌。由于这些实体的治疗和预后显著不同,准确诊断就变得更加重要。该病例强调临床医生和病理医生需要更好地协作,除常规组织病理学外,还需使用组织化学染色和免疫组织化学来得出最终诊断。对患者进行密切随访以监测肿瘤复发至关重要。

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Aggressive osteoblastoma of the acetabulum: A diagnostic dilemma.髋臼侵袭性骨母细胞瘤:诊断难题。
J Clin Orthop Trauma. 2018 Jun;9(Suppl 2):S21-S25. doi: 10.1016/j.jcot.2017.09.007. Epub 2017 Sep 18.

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