Kenan S, Floman Y, Robin G C, Laufer A
Clin Orthop Relat Res. 1985 May(195):294-8.
A recurrent osteoblastoma involving the acetabulum in a 27-year-old woman was found to be locally aggressive and histologically appeared to become more anaplastic with each recurrence. However, there was no evidence of distant metastases. Similar cases have been reported under such names as pseudomalignant or malignant osteoblastoma. In view of the prolonged clinical course without evidence of distal metastases, the term "aggressive osteoblastoma" seems to be more appropriate. The treatment of choice for such tumors should be further en bloc resection, avoiding the morbidity and possible mortality of the chemotherapy demanded by true malignant tumor of bone, as well as unnecessary ablative surgery.
一名27岁女性髋臼复发性骨母细胞瘤被发现具有局部侵袭性,且在组织学上每次复发时似乎都变得更具间变性。然而,没有远处转移的证据。类似病例曾以假性恶性或恶性骨母细胞瘤等名称报道。鉴于临床病程较长且无远处转移证据,“侵袭性骨母细胞瘤”这一术语似乎更为合适。此类肿瘤的首选治疗方法应是进一步整块切除,避免因骨真性恶性肿瘤所需化疗带来的发病率和可能的死亡率,以及不必要的根治性手术。