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本文引用的文献

1
Dasatinib Induced Avascular Necrosis of Femoral Head in Adult Patient with Chronic Myeloid Leukemia.达沙替尼诱发慢性粒细胞白血病成年患者股骨头缺血性坏死
Clin Med Insights Blood Disord. 2015 Jul 23;8:19-23. doi: 10.4137/CMBD.S24628. eCollection 2015.
2
Imatinib-induced avascular necrosis of femur in childhood chronic myeloid leukemia.伊马替尼致儿童慢性髓性白血病股骨缺血性坏死
Pediatr Hematol Oncol. 2014 Apr;31(3):268-70. doi: 10.3109/08880018.2013.862588. Epub 2014 Jan 2.
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Avascular necrosis of femoral head as the initial manifestation of CML.
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Chronic myeloid leukemia presenting with avascular necrosis of femur head.以股骨头缺血性坏死为表现的慢性髓性白血病
J Assoc Physicians India. 2003 Feb;51:214-5.
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Avascular necrosis of the femoral head in chronic myeloid leukemia patients treated with interferon-alpha: a synergistic correlation?
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6
Is avascular necrosis of the femoral head the result of inhibition of angiogenesis?股骨头缺血性坏死是血管生成受抑制的结果吗？
Med Hypotheses. 1997 Dec;49(6):497-500. doi: 10.1016/s0306-9877(97)90067-0.
7
Avascular necrosis of the femoral head as a complication of chronic myelogenous leukaemia.作为慢性粒细胞白血病并发症的股骨头缺血性坏死。
Skeletal Radiol. 1996 Oct;25(7):696-8. doi: 10.1007/s002560050163.
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Chronic myeloid leukaemia presenting as femoral head necrosis.以股骨头坏死为表现的慢性髓性白血病
Scand J Haematol. 1984 Apr;32(4):376-8. doi: 10.1111/j.1600-0609.1984.tb00691.x.
9
Avascular bone necrosis in an untreated case of chronic myelogenous leukemia.慢性粒细胞白血病未经治疗病例中的无血管性骨坏死。
Skeletal Radiol. 1988;17(5):353-5. doi: 10.1007/BF00367182.

尼罗替尼诱发一名成年慢性髓性白血病患者出现股骨头缺血性坏死。

Nilotinib induced avascular necrosis of femoral head in an adult chronic myeloid leukemia patient.

作者信息

Thekkudan Shinto Francis, Nityanand Soniya

机构信息

Department of Hematology, Sanjay Gandhi Post Graduate Institute of Medical Sciences, Lucknow, 226014, Uttar Pradesh, India.

出版信息

J Clin Orthop Trauma. 2018 Jun;9(Suppl 2):S26-S28. doi: 10.1016/j.jcot.2017.11.015. Epub 2017 Nov 24.

DOI:10.1016/j.jcot.2017.11.015
PMID:29928099
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6008635/
Abstract

We report a rare case of avascular necrosis of femoral head (AVNFH) in an adult chronic myeloid leukemia - chronic phase (CML-CP) patient during due course of therapy with second line Tyrosine Kinase Inhibitor (TKI), Nilotinib. A high index of clinical suspicion should be kept in any symptomatic CML patient on TKI's.

摘要

我们报告了一例罕见的成年慢性髓性白血病慢性期（CML-CP）患者在使用二线酪氨酸激酶抑制剂（TKI）尼罗替尼进行治疗的过程中发生股骨头缺血性坏死（AVNFH）的病例。对于任何接受TKI治疗且出现症状的CML患者，都应保持高度的临床怀疑。