Gibson J, Joshua D E, Collis D, Kronenberg H
Scand J Haematol. 1984 Apr;32(4):376-8. doi: 10.1111/j.1600-0609.1984.tb00691.x.
A 17-year-old male whose initial presentation of chronic myeloid leukaemia (CML) was necrosis of the right femoral head is reported. This is the first case report to our knowledge of CML presenting with such a lesion and is of further interest in that almost all reported cases of destructive bony lesions in this disease have been associated with blast transformation. Our patient in contrast has remained in stable chronic phase for over 30 months.
报告了一名17岁男性，其慢性髓系白血病（CML）的最初表现为右股骨头坏死。据我们所知，这是首例CML出现此类病变的病例报告，并且更有意思的是，该疾病中几乎所有报道的骨破坏性病变病例都与原始细胞转化有关。相比之下，我们的患者已处于稳定的慢性期超过30个月。
