Leone J, Vilque J P, Pignon B, Marcus C, Pennaforte J L, Eschard J P, Etienne J C
Department of Rheumatology, CHU R. Debré, Reims, France.
Skeletal Radiol. 1996 Oct;25(7):696-8. doi: 10.1007/s002560050163.
A 17-year-old male patient complaining of intense pain in his right hip was found to be suffering from chronic myelogenous leukaemia. Preliminary X-rays and bone scintigraphy did not suggest avascular necrosis of the femoral head. Magnetic resonance imaging (MRI) did, however, reveal leukaemic infiltration of the femoral neck and generalised ischeamia in the femoral head. Further, MRI carried out 4 months later disclosed typical signs of osteonecrosis, despite previous indications of an improvement under chemotherapy. Flattening of the head of the femur appeared in radiographs taken in the 9th month. In the 12th month, recurrence of pain made it necessary to perform a total hip arthroplasty. Anatomo-pathological investigation confirmed both the necrosis and the leukaemic invasion.
一名17岁男性患者因右髋部剧痛前来就诊，被诊断为慢性粒细胞白血病。初步的X线和骨闪烁显像未提示股骨头缺血性坏死。然而，磁共振成像（MRI）显示股骨颈有白血病浸润，股骨头出现广泛性缺血。此外，尽管之前有化疗后病情改善的迹象，但4个月后进行的MRI显示出典型的骨坏死征象。第9个月拍摄的X线片显示股骨头变平。第12个月，疼痛复发，不得不进行全髋关节置换术。解剖病理学检查证实了坏死和白血病浸润。
