Ngo Nhuan, Susa Michiro, Nakagawa Takahiro, Kawahara Yo, Sato Chiaki, Horiuchi Keisuke, Kumazawa Fumihisa, Shimazaki Hideyuki, Anazawa Ukei, Chiba Kazuhiro
Department of Orthopedic Surgery, National Defense Medical College, Tokorozawa, Japan.
Department of Orthopaedics and Rehabilitations, University of Medicine and Pharmacy at Ho Chi Minh City, Ho Chi Minh City, Vietnam.
Case Rep Oncol. 2018 May 17;11(2):298-304. doi: 10.1159/000489255. eCollection 2018 May-Aug.
Nodular hidradenoma (NH) is a benign adnexal tumor that arises from either eccrine or apocrine sweat glands. NH can originate from any cutaneous site, but the most common sites are the head and anterior surface of the trunk, with very rare cases in the extremities. Long-standing NH has been reported to undergo malignant transformation to malignant NH (MNH); however, its occurrence in the lower leg is extremely rare with only one other case reported to date. In this report, we present a rare case of MNH occurring in the lower leg which was resected with the intent to make a diagnosis. At the final follow-up after 11 months, no local recurrence or metastasis has been observed.
结节性汗腺瘤（NH）是一种起源于小汗腺或大汗腺的良性附属器肿瘤。NH可起源于任何皮肤部位，但最常见的部位是头和躯干前表面，四肢极为罕见。据报道，长期存在的NH可发生恶性转化为恶性结节性汗腺瘤（MNH）；然而，其在下腿部的发生极为罕见，迄今为止仅报道过一例。在本报告中，我们展示了一例发生在下腿部的罕见MNH病例，该病例经手术切除以明确诊断。在11个月后的最终随访中，未观察到局部复发或转移。
