Vincken Walter, Levy Mark L, Scullion Jane, Usmani Omar S, Dekhuijzen P N Richard, Corrigan Chris J
Respiratory Division, University Hospital Brussels (UZ Brussel), Vrije Universiteit Brussel, Brussels, Belgium.
Harrow Primary Care Trust, London, UK.
ERJ Open Res. 2018 Jun 18;4(2). doi: 10.1183/23120541.00065-2018. eCollection 2018 Apr.
We present an extensive review of the literature to date pertaining to the rationale for using a spacer/valved holding chamber (VHC) to deliver inhaled therapy from a pressurised, metered-dose inhaler, a discussion of how the properties of individual devices may vary according to their physical characteristics and materials of manufacture, the potential risks and benefits of ancillaries such as valves, and the evidence that they contribute tangibly to the delivery of therapy. We also reiterate practical recommendations for the correct usage and maintenance of spacers/VHCs, which we trust offer practical help and advice to patients and healthcare professionals alike.
我们对迄今为止有关使用间隔器/带阀储物罐（VHC）从压力定量吸入器输送吸入疗法的基本原理的文献进行了广泛综述，讨论了各个装置的特性如何根据其物理特征和制造材料而有所不同，诸如阀门等附件的潜在风险和益处，以及它们对治疗输送有切实贡献的证据。我们还重申了关于间隔器/VHC正确使用和维护的实用建议，相信这些建议能为患者和医疗保健专业人员提供实际帮助和指导。
