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Nod-Like Receptor Pyrin-Containing Protein 6 (NLRP6) Is Up-regulated in Ileal Crohn's Disease and Differentially Expressed in Goblet Cells.

作者信息

Ranson Nicole, Veldhuis Mark, Mitchell Brent, Fanning Scott, Cook Anthony L, Kunde Dale, Eri Rajaraman

机构信息

School of Health Sciences, University of Tasmania, Launceston, Tasmania, Australia.

Launceston General Hospital, Launceston, Tasmania, Australia.

出版信息

Cell Mol Gastroenterol Hepatol. 2018 Mar 13;6(1):110-112.e8. doi: 10.1016/j.jcmgh.2018.03.001. eCollection 2018.

DOI:10.1016/j.jcmgh.2018.03.001
PMID:29928676
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6007817/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dd48/6007817/b26901962216/fx4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dd48/6007817/21af1887cb0e/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dd48/6007817/e0b571e269c5/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dd48/6007817/acfc46003ebf/fx1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dd48/6007817/6750294ead4c/fx2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dd48/6007817/0039e24d4af3/fx3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dd48/6007817/b26901962216/fx4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dd48/6007817/21af1887cb0e/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dd48/6007817/e0b571e269c5/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dd48/6007817/acfc46003ebf/fx1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dd48/6007817/6750294ead4c/fx2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dd48/6007817/0039e24d4af3/fx3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dd48/6007817/b26901962216/fx4.jpg

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Nod-Like Receptor Pyrin-Containing Protein 6 (NLRP6) Is Up-regulated in Ileal Crohn's Disease and Differentially Expressed in Goblet Cells.含吡啉结构域的NOD样受体蛋白6(NLRP6)在回肠克罗恩病中上调且在杯状细胞中差异表达。
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2
A sentinel goblet cell guards the colonic crypt by triggering Nlrp6-dependent Muc2 secretion.哨兵杯状细胞通过触发依赖于 Nlrp6 的 Muc2 分泌来保护结肠隐窝。
Science. 2016 Jun 24;352(6293):1535-42. doi: 10.1126/science.aaf7419.
3
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Int J Mol Sci. 2023 Sep 25;24(19):14511. doi: 10.3390/ijms241914511.
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Commun Biol. 2022 Jun 1;5(1):524. doi: 10.1038/s42003-022-03491-w.
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