Stegner H E
Geburtshilfe Frauenheilkd. 1985 Jul;45(7):425-30. doi: 10.1055/s-2008-1036348.
Ovarian tumours form a broad spectrum of histological types which reflect significant differences with regard to their biological behaviour and their responsiveness to radiological and cytostatical therapy. Precise subclassification is a precondition for selective therapy. A special subclass of tumours is represented by so-called borderline tumours which form a significant proportion of the overall group of epithelian ovarian neoplasms. Borderline tumours are histologically defined tumours which are neither fully benign nor overtly malignant. Though capable to metastasise they are of low malignant potential and favourable prognosis. In clinical statistics borderline tumours should be registered as a special entity. Within the ordinary group of malignant epithelial tumours histological grading has proven to be of prognostic significance. Amongst a great spectrum of useful cyto-histological criteria, nuclear polymorphism. The number of mitoses, and necrosis are the most important predictive factors.
卵巢肿瘤具有广泛的组织学类型，这反映出它们在生物学行为以及对放射治疗和细胞抑制疗法的反应方面存在显著差异。精确的亚分类是选择性治疗的前提条件。肿瘤的一个特殊亚类由所谓的交界性肿瘤代表，它们在卵巢上皮性肿瘤的总体中占相当大的比例。交界性肿瘤是组织学上定义的肿瘤，既不完全良性也不明显恶性。尽管它们有转移能力，但恶性潜能低，预后良好。在临床统计中，交界性肿瘤应作为一个特殊实体进行登记。在普通的恶性上皮性肿瘤组中，组织学分级已被证明具有预后意义。在众多有用的细胞组织学标准中，核多形性、有丝分裂数和坏死是最重要的预测因素。
