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[临床预后因素在晚期卵巢癌治疗中的重要性]

[Importance of clinically prognostic factors in the treatment of advanced ovarian carcinoma].

作者信息

Albrecht M, Goepel E, Simon W E, Trams G

出版信息

Geburtshilfe Frauenheilkd. 1985 Jul;45(7):482-7. doi: 10.1055/s-2008-1036357.

DOI:10.1055/s-2008-1036357
PMID:2993094
Abstract

25 patients with stage III and IV ovarian carcinoma were treated with radical surgery and postoperative chemotherapy. Analysis of the disease-free intervals and the survival rates indicated significant differences related to the stage of the disease. Furthermore patients with minimal residual disease (tumor mass less than 2 cm in diameter) had a far better prognosis than patients with extensive residual disease (greater than 3 cm). No correlation could be demonstrated between histological grading, in vitro proliferation rates, hormone receptor status, type of postoperative chemotherapy and survival rates.

摘要

25例III期和IV期卵巢癌患者接受了根治性手术和术后化疗。对无病间期和生存率的分析表明,与疾病分期存在显著差异。此外,残留病灶最小(肿瘤直径小于2厘米)的患者预后远优于残留病灶广泛(大于3厘米)的患者。组织学分级、体外增殖率、激素受体状态、术后化疗类型与生存率之间未显示出相关性。

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