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操纵子映射器:一个用于在细菌和古菌基因组中精确识别操纵子的网络服务器。

Operon-mapper: a web server for precise operon identification in bacterial and archaeal genomes.

机构信息

Department of Developmental Genetics and Molecular Physiology, Universidad Nacional Autónoma de México, Cuernavaca, Morelos, México.

Department of Molecular Microbiology, Instituto de Biotecnología, Universidad Nacional Autónoma de México, Cuernavaca, Morelos, México.

出版信息

Bioinformatics. 2018 Dec 1;34(23):4118-4120. doi: 10.1093/bioinformatics/bty496.

Abstract

SUMMARY

Operon-mapper is a web server that accurately, easily and directly predicts the operons of any bacterial or archaeal genome sequence. The operon predictions are based on the intergenic distance of neighboring genes as well as the functional relationships of their protein-coding products. To this end, Operon-mapper finds all the ORFs within a given nucleotide sequence, along with their genomic coordinates, orthology groups and functional relationships. We believe that Operon-mapper, due to its accuracy, simplicity and speed, as well as the relevant information that it generates, will be a useful tool for annotating and characterizing genomic sequences.

AVAILABILITY AND IMPLEMENTATION

http://biocomputo.ibt.unam.mx/operon_mapper/.

摘要

摘要

Operon-mapper 是一个网络服务器,可准确、轻松、直接地预测任何细菌或古菌基因组序列的操纵子。操纵子预测基于相邻基因的基因间距离以及它们蛋白质编码产物的功能关系。为此,Operon-mapper 在给定的核苷酸序列中找到所有的 ORF,以及它们的基因组坐标、直系同源群和功能关系。我们相信,由于其准确性、简单性和速度,以及它生成的相关信息,Operon-mapper 将成为注释和表征基因组序列的有用工具。

可用性和实现

http://biocomputo.ibt.unam.mx/operon_mapper/。

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