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本文引用的文献

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Computational operon prediction in whole-genomes and metagenomes.全基因组和宏基因组中的计算操纵子预测。
Brief Funct Genomics. 2017 Jul 1;16(4):181-193. doi: 10.1093/bfgp/elw034.
2
Fast and sensitive protein alignment using DIAMOND.使用 DIAMOND 进行快速灵敏的蛋白质比对。
Nat Methods. 2015 Jan;12(1):59-60. doi: 10.1038/nmeth.3176. Epub 2014 Nov 17.
3
Prokka: rapid prokaryotic genome annotation.Prokka:快速的原核生物基因组注释。
Bioinformatics. 2014 Jul 15;30(14):2068-9. doi: 10.1093/bioinformatics/btu153. Epub 2014 Mar 18.
4
ProOpDB: Prokaryotic Operon DataBase.ProOpDB:原核操纵子数据库。
Nucleic Acids Res. 2012 Jan;40(Database issue):D627-31. doi: 10.1093/nar/gkr1020. Epub 2011 Nov 16.
5
Accelerated Profile HMM Searches.加速轮廓隐马尔可夫模型搜索。
PLoS Comput Biol. 2011 Oct;7(10):e1002195. doi: 10.1371/journal.pcbi.1002195. Epub 2011 Oct 20.
6
High accuracy operon prediction method based on STRING database scores.基于 STRING 数据库评分的高精度操纵子预测方法。
Nucleic Acids Res. 2010 Jul;38(12):e130. doi: 10.1093/nar/gkq254. Epub 2010 Apr 12.
7
Prodigal: prokaryotic gene recognition and translation initiation site identification.普罗迪格:原核基因识别和翻译起始位点鉴定。
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8
DOOR: a database for prokaryotic operons.DOOR:一个原核生物操纵子数据库。
Nucleic Acids Res. 2009 Jan;37(Database issue):D459-63. doi: 10.1093/nar/gkn757. Epub 2008 Nov 6.
9
OperonDB: a comprehensive database of predicted operons in microbial genomes.操纵子数据库:微生物基因组中预测操纵子的综合数据库。
Nucleic Acids Res. 2009 Jan;37(Database issue):D479-82. doi: 10.1093/nar/gkn784. Epub 2008 Oct 23.
10
STRING 8--a global view on proteins and their functional interactions in 630 organisms.STRING 8——关于630种生物中蛋白质及其功能相互作用的全局视图。
Nucleic Acids Res. 2009 Jan;37(Database issue):D412-6. doi: 10.1093/nar/gkn760. Epub 2008 Oct 21.

操纵子映射器:一个用于在细菌和古菌基因组中精确识别操纵子的网络服务器。

Operon-mapper: a web server for precise operon identification in bacterial and archaeal genomes.

机构信息

Department of Developmental Genetics and Molecular Physiology, Universidad Nacional Autónoma de México, Cuernavaca, Morelos, México.

Department of Molecular Microbiology, Instituto de Biotecnología, Universidad Nacional Autónoma de México, Cuernavaca, Morelos, México.

出版信息

Bioinformatics. 2018 Dec 1;34(23):4118-4120. doi: 10.1093/bioinformatics/bty496.

DOI:10.1093/bioinformatics/bty496
PMID:29931111
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6247939/
Abstract

SUMMARY

Operon-mapper is a web server that accurately, easily and directly predicts the operons of any bacterial or archaeal genome sequence. The operon predictions are based on the intergenic distance of neighboring genes as well as the functional relationships of their protein-coding products. To this end, Operon-mapper finds all the ORFs within a given nucleotide sequence, along with their genomic coordinates, orthology groups and functional relationships. We believe that Operon-mapper, due to its accuracy, simplicity and speed, as well as the relevant information that it generates, will be a useful tool for annotating and characterizing genomic sequences.

AVAILABILITY AND IMPLEMENTATION

http://biocomputo.ibt.unam.mx/operon_mapper/.

摘要

摘要

Operon-mapper 是一个网络服务器,可准确、轻松、直接地预测任何细菌或古菌基因组序列的操纵子。操纵子预测基于相邻基因的基因间距离以及它们蛋白质编码产物的功能关系。为此,Operon-mapper 在给定的核苷酸序列中找到所有的 ORF,以及它们的基因组坐标、直系同源群和功能关系。我们相信,由于其准确性、简单性和速度,以及它生成的相关信息,Operon-mapper 将成为注释和表征基因组序列的有用工具。

可用性和实现

http://biocomputo.ibt.unam.mx/operon_mapper/。