Department of Food Science and Engineering, School of Agriculture and Biology, Shanghai Jiao Tong University, Shanghai, China.
Institute of Food and Marine Bioresources, College of Biological Science and Technology, Fuzhou University, Fuzhou, China.
J Sci Food Agric. 2019 Jan 30;99(2):536-545. doi: 10.1002/jsfa.9212. Epub 2018 Aug 16.
To reducing the massive marine pollution and resource waste caused by octopus scraps, we developed a novel octopus scraps protein hydrolysate (OSPH), which displays calcium-chelating activity, and we investigated the chelating interaction and calcium bioavailability of OSPH-Ca.
The structural properties of amido and carboxy groups indicated that they could be the reaction sites for chelation. The particle radius of OSPH increased by 32.25 nm after the calcium chelated with OSPH, indicating intramolecular and intermolecular folding and aggregating. The enthalpy of OSPH increased by 0.8323 after chelation, showing that bands of OSPH-Ca needed more thermal energy to be destroyed than OSPH. Meanwhile, the chelate showed remarkable stability and absorbability under either acidic or basic conditions, which favored calcium absorption in the gastrointestinal tracts of humans. The calcium intake of OSPH-Ca increased by 41% when compared with that of CaCl . In particular, OSPH-Ca could protect calcium ions from precipitation caused by dietary inhibitors tannic acid and phytate, while calcium uptake efficiency remained at 3.35 and 1.68 times higher than that of CaCl .
These findings revealed the feasibility of transforming octopus scraps into a novel functional calcium chelate based on peptides, promoting environmental sustainability. © 2018 Society of Chemical Industry.
为减少章鱼废弃物造成的海洋污染和资源浪费，我们开发了一种新型的章鱼废弃物蛋白水解物（OSPH），具有钙螯合活性，并研究了 OSPH-Ca 的螯合作用和钙生物利用度。
氨基和羧基的结构特性表明它们可能是螯合的反应位点。OSPH 与钙螯合后，其粒径增加了 32.25nm，表明发生了分子内和分子间的折叠和聚集。螯合后 OSPH 的焓增加了 0.8323，表明 OSPH-Ca 的键需要更多的热能才能被破坏。同时，在酸性或碱性条件下，螯合物都具有显著的稳定性和吸收性，有利于人体胃肠道对钙的吸收。与 CaCl 相比，OSPH-Ca 的钙摄入量增加了 41%。特别是，OSPH-Ca 可以防止膳食抑制剂单宁酸和植酸引起的钙离子沉淀，而钙的摄取效率仍保持在 CaCl 的 3.35 和 1.68 倍。
这些发现揭示了基于肽将章鱼废弃物转化为新型功能性钙螯合物的可行性，促进了环境的可持续性。© 2018 化学工业协会。
