Operative Dentistry Department, Faculty of Dentistry, King Abdulaziz University, Jeddah, Saudi Arabia; Conservative Dentistry Department, Faculty of Dentistry, Alexandria University, Alexandria, Egypt.
Department of Orthodontics, Faculty of Dentistry, King Abdulaziz University, Jeddah, Saudi Arabia; Alexandria University, Alexandria, Egypt.
J Dent. 2018 Sep;76:52-57. doi: 10.1016/j.jdent.2018.06.006. Epub 2018 Jun 19.
To compare the remineralization efficacy of using the MI paste plus according to manufacturer's instructions to MI varnish and to using a modified method of MI-paste plus application.
100 enamel specimens were obtained from the buccal and lingual surfaces of 50 extracted human non-caries third molars. All specimens were challenged by a buffered demineralization solution for 4 days, and were divided in 4 groups with 25 specimens in each group. 25 demineralized specimens had MI paste plus applied for 4 min and then wiped out (MI), 25 specimens had MI paste applied followed by application of SE-bonding agent (MI + Bond), 25 specimens had MI Varnish applied according to manufacturer instructions (MI Varnish) the rest of specimens served as controls (C). All specimens were stored for 7 days in artificial saliva. All specimens had their surface hardness (SH) measured by micro-hardness tester before/after the acidic challenge and after the treatment procedures. After the SH test all specimens were crosssectioned to obtain 100-150 micron thickness specimens to observe the lesion depth before/after treatment by the TMR (Transverse Micro Radiography) technique.
TMR experiment showed that (MI + Bond) and (MI varnish) groups recorded significant decrease in lesion depth and mineral loss of the tested subsurface lesion p < 0.05. (MI + Bond) group scored the highest significant regain of surface micro hardness results p < 0.05.
(MI varnish) and the modified application of MI paste are methods that can increase the efficacy of CPP-ACP in remineralizing the enamel surface lesions.
比较按说明书使用 MI 糊剂加和 MI 漆以及使用改良的 MI 糊剂加应用方法的再矿化效果。
从 50 颗拔除的非龋第三磨牙的颊舌面获得 100 个釉质标本。所有标本均用缓冲脱矿液挑战 4 天，然后将其分为 4 组，每组 25 个标本。25 个脱矿标本用 MI 糊剂加处理 4 分钟，然后擦拭（MI），25 个标本用 MI 糊剂加 SE 结合剂处理（MI + Bond），25 个标本按说明书涂 MI 漆（MI Varnish），其余标本作为对照（C）。所有标本均在人工唾液中储存 7 天。所有标本在酸性挑战前后和处理程序后用显微硬度计测量表面硬度（SH）。SH 测试后，所有标本均进行横断微放射照相术（TMR）观察治疗前后的病变深度。
TMR 实验表明，（MI + Bond）和（MI 漆）组记录的病变深度和测试亚表面病变的矿物质损失显著减少，p < 0.05。（MI + Bond）组表面显微硬度结果的显著恢复最高，p < 0.05。
（MI 漆）和改良的 MI 糊剂加应用是可以增加 CPP-ACP 对釉质表面病变再矿化效果的方法。
