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与全科医生替代边缘性维生素B12缺乏倾向相关的因素。

Factors correlating to the propensity of general practitioners to substitute borderline vitamin B12 deficiency.

作者信息

Cham Grace, Davis Nichola, Strivens Edward, Traves Aileen, Manypeney Grant, Gunnarsson Ronny

机构信息

a Cairns Clinical School, College of Medicine and Dentistry , James Cook University , Australia.

b Older Persons and Subacute Services , Cairns and Hinterland Hospital and Health Service , Cairns , Queensland , Australia.

出版信息

Scand J Prim Health Care. 2018 Sep;36(3):242-248. doi: 10.1080/02813432.2018.1487522. Epub 2018 Jun 22.

Abstract

OBJECTIVE

This study aims to identify factors which correlate to the propensity of general practitioners (GPs) to prescribe supplementation for borderline vitamin B12 deficiency.

DESIGN

Cross-sectional surveys were distributed in person.

SETTING

Conferences held in Cairns, Palm Cove Beach, Mt Isa; educational meetings in Atherton; and meetings with individual general practices within the Cairns and Hinterland region. All located in Queensland, Australia.

SUBJECTS

128 practicing GP specialists and registrars (practitioners in training).

MAIN OUTCOME MEASURES

Responses to the Likert scale statements with its five options scaling from 'strongly disagree' to 'strongly agree' were recoded to have binary outcomes for analysis.

RESULTS

A survey response rate of 89% was achieved. Participants who felt patient demands influence the management of borderline vitamin B12 deficiency were more likely to prescribe supplementation (OR 2.4, p = 0.037). Participants who perceived an overuse of vitamin B12 were less likely to prescribe B12 (OR 0.39, p = 0.019). Participants who often saw patients with vitamin B12 deficiency were less likely to request for the complementary biomarkers plasma methylmalonic acid or total homocysteine (OR 0.41, p = 0.045).

CONCLUSIONS

The identified disparity to prescribe vitamin B12 for borderline deficiency may be described as an attempt in the GP collective to seek a balance between being the patient's or the society's doctor. We propose that relevant authorities try to reduce this disparity by describing a management strategy for borderline vitamin B12 deficiency. Key points General practitioners hold different thresholds for commencing supplementation in cases of borderline vitamin B12 deficiency. Participants from Australia were asked to fill out a cross-sectional survey to explore factors which correlate with the propensity to prescribe in clinical practice. Our study identified that patient demands and a practitioner's perception of whether there is an overuse of vitamin B12 in the community influenced the propensity to treat for deficiency. The results give insight into reasons for initiating supplementation, and will help inform general practitioners on their current management.

摘要

目的

本研究旨在确定与全科医生(GP)为边缘性维生素B12缺乏症患者开补充剂倾向相关的因素。

设计

采用面对面发放横断面调查问卷的方式。

地点

在凯恩斯、棕榈湾海滩、芒特艾萨举办的会议;在阿瑟顿举办的教育会议;以及在凯恩斯和内陆地区与各个全科诊所的会议。所有地点均位于澳大利亚昆士兰州。

研究对象

128名执业全科医生专家和注册医生(正在接受培训的从业者)。

主要观察指标

对李克特量表陈述的回答,其五个选项从“强烈不同意”到“强烈同意”,重新编码以产生二元结果进行分析。

结果

调查回复率达到89%。认为患者需求会影响边缘性维生素B12缺乏症管理的参与者更有可能开补充剂(比值比2.4,p = 0.037)。认为维生素B12存在过度使用情况的参与者开维生素B12补充剂的可能性较小(比值比0.39,p = 0.019)。经常诊治维生素B12缺乏症患者的参与者要求检测补充生物标志物血浆甲基丙二酸或总同型半胱氨酸的可能性较小(比值比0.41,p = 0.045)。

结论

在为边缘性缺乏症开维生素B12补充剂方面存在的差异,可被描述为全科医生群体试图在作为患者的医生还是社会的医生之间寻求平衡。我们建议相关当局通过描述边缘性维生素B12缺乏症的管理策略来减少这种差异。要点 全科医生在开始为边缘性维生素B12缺乏症患者补充时持有不同的阈值。来自澳大利亚的参与者被要求填写一份横断面调查问卷,以探索与临床实践中开补充剂倾向相关的因素。我们的研究发现,患者需求以及从业者对社区中维生素B12是否存在过度使用的认知会影响治疗缺乏症的倾向。这些结果深入揭示了开始补充的原因,并将有助于告知全科医生他们目前的管理方式。

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Vitamin B12 deficiency in the elderly: is it worth screening?老年人维生素B12缺乏:值得筛查吗?
Hong Kong Med J. 2015 Apr;21(2):155-64. doi: 10.12809/hkmj144383. Epub 2015 Mar 10.

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