College of Environment and Plant Protection, Hainan University, Haikou 570228, China.
College of Environment and Plant Protection, Hainan University, Haikou 570228, China.
Pestic Biochem Physiol. 2018 May;147:145-152. doi: 10.1016/j.pestbp.2017.08.011. Epub 2017 Aug 14.
Harmful algal blooms (HABs) has been a serious problem in recent years, because of large quantities of cyanobacterial in eutrophic water. We studied the effects of 3,4-Dihydroxybenzalacetone (DBL) and other four compounds (vanillic acid, ferulic acid, 3,5-Dichlorophenol and cupric sulfate) on Microcystis aeruginosa. The results showed that the growth of M. aeruginosa was significantly inhibited by all tested compounds with a half maximal effect concentration (EC) of 5.2, 22.8, 54.7, 1.5, 0.3μg/mL, respectively. Our data also demonstrated that DBL triggered the generation of superoxide anion radicals (O). The O might induce a lipid peroxidation which may change cell membrane penetrability, thereby leading to the eventual death of M. aeruginosa. In addition, DBL may has few toxic to aquatic species as indicated by its 96h half maximum lethal concentration value to zebrafish (Danio rerio) was far higher than 128μg/mL. Our current study further provides evidence that some phenolic acids such as DBL may be a potential effective solution for aquatic management.
有害藻华（HAB）近年来一直是一个严重的问题，因为富营养化水中存在大量的蓝藻。我们研究了 3,4-二羟基苯乙酮（DBL）和其他四种化合物（香草酸、阿魏酸、3,5-二氯苯酚和硫酸铜）对铜绿微囊藻的影响。结果表明，所有测试化合物均显著抑制铜绿微囊藻的生长，其半数最大效应浓度（EC）分别为 5.2、22.8、54.7、1.5 和 0.3μg/mL。我们的数据还表明，DBL 引发了超氧阴离子自由基（O）的产生。O 可能诱导脂质过氧化，从而改变细胞膜通透性，导致铜绿微囊藻最终死亡。此外，DBL 对水生生物的毒性可能较小，因为其对斑马鱼（Danio rerio）的 96 小时半数最大致死浓度值远高于 128μg/mL。我们目前的研究进一步提供了证据，表明一些酚酸类物质，如 DBL，可能是一种潜在的有效水生管理解决方案。
