Turner Ralph M, Ma Qinli, Lorig Kate, Greenberg Jay, DeVries Andrea R
HealthCore, Inc, Wilmington, DE, United States.
Stanford Patient Education Research Center, Palo Alto, CA, United States.
J Med Internet Res. 2018 Jun 22;20(6):e207. doi: 10.2196/jmir.9225.
An estimated 30.3 million Americans have diabetes mellitus. The US Department of Health and Human Services created national objectives via its Healthy People 2020 initiative to improve the quality of life for people who either have or are at risk for diabetes mellitus, and hence, lower the personal and national economic burden of this debilitating chronic disease. Diabetes self-management education interventions are a primary focus of this initiative.
The aim of this study was to evaluate the impact of the Better Choices Better Health Diabetes (BCBH-D) self-management program on comorbid illness related to diabetes mellitus, health care utilization, and cost.
A propensity score matched two-group, pre-post design was used for this study. Retrospective administrative medical and pharmacy claims data from the HealthCore Integrated Research Environment were used for outcome variables. The intervention cohort included diabetes mellitus patients who were recruited to a diabetes self-management program. Control cohort subjects were identified from the HealthCore Integrated Research Environment by at least two diabetes-associated claims (International Classification of Diseases-Ninth Revision, ICD-9 250.xx) within 2 years before the program launch date (October 1, 2011-September 30, 2013) but did not participate in BCBH-D. Controls were matched to cases in a 3:1 propensity score match. Outcome measures included pre- and postintervention all-cause and diabetes-related utilization and costs. Cost outcomes are reported as least squares means. Repeated measures analyses (generalized estimating equation approach) were conducted for utilization, comorbid conditions, and costs.
The program participants who were identified in HealthCore Integrated Research Environment claims (N=558) were matched to a control cohort of 1669 patients. Following the intervention, the self-management cohort experienced significant reductions for diabetes mellitus-associated comorbid conditions, with the postintervention disease burden being significantly lower (mean 1.6 [SD 1.6]) compared with the control cohort (mean 2.1 [SD 1.7]; P=.001). Postintervention all-cause utilization was decreased in the intervention cohort compared with controls with -40/1000 emergency department visits vs +70/1000; P=.004 and -5780 outpatient visits per 1000 vs -290/1000; P=.001. Unadjusted total all-cause medical cost was decreased by US $2207 in the intervention cohort compared with a US $338 decrease in the controls; P=.001. After adjustment for other variables through structural equation analysis, the direct effect of the BCBH-D was -US $815 (P=.049).
Patients in the BCBH-D program experienced reduced all-cause health care utilization and costs. Direct cost savings were US $815. Although encouraging, given the complexity of the patient population, further study is needed to cross-validate the results.
据估计,美国有3030万人患有糖尿病。美国卫生与公众服务部通过其“健康人民2020”倡议制定了国家目标,以改善糖尿病患者或糖尿病高危人群的生活质量,从而减轻这种使人衰弱的慢性病的个人和国家经济负担。糖尿病自我管理教育干预措施是该倡议的主要重点。
本研究的目的是评估“更佳选择,更优健康糖尿病(BCBH-D)”自我管理项目对糖尿病相关合并症、医疗保健利用和成本的影响。
本研究采用倾向得分匹配的两组前后设计。来自HealthCore综合研究环境的回顾性行政医疗和药房索赔数据用作结果变量。干预队列包括被招募参加糖尿病自我管理项目的糖尿病患者。对照队列受试者是在项目启动日期(2011年10月1日至2013年9月30日)前2年内通过HealthCore综合研究环境中至少两项与糖尿病相关的索赔(国际疾病分类第九版,ICD-9 250.xx)确定的,但未参加BCBH-D。对照组与病例以3:1的倾向得分进行匹配。结果指标包括干预前后的全因和糖尿病相关的利用情况及成本。成本结果以最小二乘均值报告。对利用情况、合并症和成本进行重复测量分析(广义估计方程法)。
在HealthCore综合研究环境索赔中确定的项目参与者(N = 558)与1669名患者的对照队列进行了匹配。干预后,自我管理队列中与糖尿病相关的合并症显著减少,干预后的疾病负担明显低于对照组(均值1.6[标准差1.6]),而对照组为(均值2.1[标准差1.7];P = 0.001)。与对照组相比,干预队列中干预后的全因利用情况有所下降,急诊就诊次数为-40/1000,而对照组为+70/1000;P = 0.004,每1000人的门诊就诊次数为-5780,而对照组为-290/1000;P = 0.001。与对照组成本下降338美元相比,干预队列中未调整的全因医疗总成本下降了2207美元;P = 0.001。通过结构方程分析对其他变量进行调整后,BCBH-D的直接效应为-815美元(P = 0.049)。
BCBH-D项目中的患者全因医疗保健利用和成本有所降低。直接成本节省为815美元。尽管令人鼓舞,但鉴于患者群体的复杂性,需要进一步研究以交叉验证结果。