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谷物制品中赭曲霉毒素 A、玉米赤霉烯酮、脱氧雪腐镰刀菌烯醇和总黄曲霉毒素的流行率和浓度:系统评价和荟萃分析。

Prevalence and concentration of ochratoxin A, zearalenone, deoxynivalenol and total aflatoxin in cereal-based products: A systematic review and meta-analysis.

机构信息

Department of Food Science, Faculty of Food Engineering, University of Campinas, Campinas, SP, Brazil.

Student Research Committee, Department of Environmental Health Engineering, School of Public Health, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

出版信息

Food Chem Toxicol. 2018 Aug;118:830-848. doi: 10.1016/j.fct.2018.06.037. Epub 2018 Jun 21.

DOI:10.1016/j.fct.2018.06.037
PMID:29935247
Abstract

This study aimed to estimate the prevalence and concentration of total aflatoxin (TAF) ochratoxin A (OTA), zearalenone (ZEN) and deoxynivalenol (DON) in bread, cornflakes, breakfast cereals and pasta-based products through meta-analysis. The required databases including (PubMed and Scopus databases) were investigated to collect data on the concentration and prevalence of mentioned mycotoxins in cereal-based products. Among 2461 explored articles in identification step, 38 articles with 9627 samples were included in the conducted meta-analysis. The prevalence and concentration of studied mycotoxins varied with the cereal-based food studied. In this context, the overall rank order of mycotoxins prevalence in the cereal foods was OTA > DON > ZEN > TAF > 15-ADON > 3-ADON. Also, the overall rank order of mycotoxins based on concentration in the cereal foods investigated was DON > ZEN > 15-ADON > OTA > 3-ADON > TAF. The findings of this meta-analysis may be useful for the building of risk assessment models aiming to derive data for the development of specific actions to reduce the exposure to OTA, ZEN, TAF, and DON through the consumption of the cereal-based products.

摘要

本研究旨在通过荟萃分析估计面包、玉米片、早餐麦片和面条产品中总黄曲霉毒素(TAF)、赭曲霉毒素 A(OTA)、玉米赤霉烯酮(ZEN)和脱氧雪腐镰刀菌烯醇(DON)的流行率和浓度。研究调查了所需的数据库(PubMed 和 Scopus 数据库),以收集有关谷物制品中提到的霉菌毒素浓度和流行率的数据。在识别步骤中探索了 2461 篇文章,有 38 篇文章(9627 个样本)纳入了进行的荟萃分析。研究霉菌毒素的流行率和浓度因研究的谷物食品而异。在这种情况下,谷物食品中霉菌毒素的总体流行率顺序为 OTA>DON>ZEN>TAF>15-ADON>3-ADON。此外,根据谷物食品中霉菌毒素浓度的总体排名顺序为 DON>ZEN>15-ADON>OTA>3-ADON>TAF。本荟萃分析的结果可能有助于建立风险评估模型,旨在通过食用谷物制品来获得数据,以制定特定行动来减少 OTA、ZEN、TAF 和 DON 的暴露。

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