硼中子俘获治疗中用于剂量评估的中子能谱测量方法研究。

Investigation of the neutron spectrum measurement method for dose evaluation in boron neutron capture therapy.

作者信息

Onishi T, Kumada H, Takada K, Naito F, Kurihara T, Sakae T

机构信息

Graduate School of Comprehensive Human Sciences, University of Tsukuba, 1-1-1 Tennoudai, Tsukuba, Ibaraki 305-8575, Japan.

Faculty of Medicine, University of Tsukuba, 1-1-1 Tennoudai, Tsukuba, Ibaraki 305-8575, Japan.

出版信息

Appl Radiat Isot. 2018 Oct;140:5-11. doi: 10.1016/j.apradiso.2018.06.004. Epub 2018 Jun 11.

DOI:10.1016/j.apradiso.2018.06.004

PMID:29936276

Abstract

In boron neutron capture therapy, it is important to evaluate the dose administered to a patient's body outside the tumour area. The exposure dose is evaluated by calculation; however, the calculated value must be validated using a measured value. The dose evaluations based on the measured neutron spectrum are investigated. Multi-foil activation, combined with a LiCaAlF scintillation detector and an imaging plate, is proposed as a measurement method. The proposed method can measure the neutron spectrum at various points quickly.

摘要

在硼中子俘获疗法中，评估给予肿瘤区域外患者身体的剂量很重要。通过计算来评估暴露剂量；然而，计算值必须用测量值进行验证。研究了基于测量中子能谱的剂量评估。提出了一种将多箔活化与LiCaAlF闪烁探测器和成像板相结合的测量方法。所提出的方法可以快速测量不同点的中子能谱。