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Why is the hydrolytic activity of acetylcholinesterase pH dependent? Kinetic study of acetylcholine and acetylthiocholine hydrolysis catalyzed by acetylcholinesterase from electric eel.

作者信息

Komersová Alena, Kovářová Markéta, Komers Karel, Lochař Václav, Čegan Alexander

机构信息

Department of Physical Chemistry, Faculty of Chemical Technology, University of Pardubice, Studentská 573, 532 10 Pardubice, Czech Republic.

Department of Physical Chemistry, Faculty of Chemical Technology, University of Pardubice, Studentská 573, 532 10 Pardubice, Czech Republic, Fax: +420-466-037-068.

出版信息

Z Naturforsch C J Biosci. 2018 Sep 25;73(9-10):345-351. doi: 10.1515/znc-2017-0134.

DOI:10.1515/znc-2017-0134
PMID:29936491
Abstract
摘要

相似文献

1
Why is the hydrolytic activity of acetylcholinesterase pH dependent? Kinetic study of acetylcholine and acetylthiocholine hydrolysis catalyzed by acetylcholinesterase from electric eel.为什么乙酰胆碱酯酶的水解活性依赖于pH值？对电鳗乙酰胆碱酯酶催化的乙酰胆碱和乙酰硫代胆碱水解的动力学研究。
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Direct determination of acetyl-enzyme intermediate in the acetylcholinesterase-catalyzed hydrolysis of acetylcholine and acetylthiocholine.在乙酰胆碱酯酶催化乙酰胆碱和乙酰硫代胆碱水解过程中对乙酰化酶中间体的直接测定。
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Arrhenius analysis of the electrophorus electricus acetylcholinesterase-catalyzed hydrolysis of acetylthiocholine.电鳗乙酰胆碱酯酶催化硫代乙酰胆碱水解的阿仑尼乌斯分析。
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Kinetics of acetylthiocholine binding to electric eel acetylcholinesterase in glycerol/water solvents of increased viscosity. Evidence for a diffusion-controlled reaction.在粘度增加的甘油/水溶剂中乙酰硫代胆碱与电鳗乙酰胆碱酯酶结合的动力学。扩散控制反应的证据。
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Kinetics of total enzymatic hydrolysis of acetylcholine and acetylthiocholine.乙酰胆碱和乙酰硫代胆碱的总酶促水解动力学
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