Zakaria Mohd Normani, Nik Othman Nik Adilah, Musa Zalilah
Audiology Programme, School of Health Sciences, Universiti Sains Malaysia, 16150, Kubang Kerian, Kelantan, Malaysia.
Department of Otorhinolaryngology (ORL), School of Medical Sciences, Universiti Sains Malaysia, 16150, Kubang Kerian, Kelantan, Malaysia.
J Otol. 2017 Mar;12(1):29-33. doi: 10.1016/j.joto.2017.02.002. Epub 2017 Feb 11.
Electrocochleography (ECochG) is valuable to diagnose Meniere's disease objectively. The aim of the present study was to provide preliminary normative data for ECochG among Asian adults. The influences of ethnicity (Malay versus Chinese) and gender on ECochG results were also studied.
Twenty-two Malay adults (10 men and 12 women) and twenty Chinese participants (10 men and 10 women) aged between 20 and 49 years participated in this study. Extratympanic ECochG (ET-ECochG) was recorded according to standard non-invasive procedure. Summating potential (SP) amplitude, action potential (AP) amplitude and SP/AP ratio were analyzed accordingly.
ET-ECochG results were found to be comparable between left and right ears (p > 0.05). No notable differences in ET-ECochG results were found between Malay and Chinese groups (p > 0.05). No significant influence of gender on ET-ECochG outcomes was also noted (p > 0.05). The derived normative data for Asian adults (84 ears) are consistent with previous reports.
The present study provides preliminary normative data for ET-ECochG among Asian adults. The ECochG components do not appear to be influenced by either ethnicity or gender. The derived normative data can be used for clinical applications and as the reference for future studies involving Asian population.
电耳蜗图(ECochG)对于客观诊断梅尼埃病很有价值。本研究的目的是提供亚洲成年人ECochG的初步规范数据。还研究了种族(马来人与华人)和性别对ECochG结果的影响。
22名年龄在20至49岁之间的马来成年人(10名男性和12名女性)和20名华人参与者(10名男性和10名女性)参与了本研究。根据标准非侵入性程序记录鼓室外ECochG(ET-ECochG)。相应地分析了总和电位(SP)振幅、动作电位(AP)振幅和SP/AP比率。
发现左耳和右耳的ET-ECochG结果具有可比性(p>0.05)。马来人群体和华人人群体之间的ET-ECochG结果未发现显著差异(p>0.05)。也未观察到性别对ET-ECochG结果有显著影响(p>0.05)。得出的亚洲成年人(84只耳)的规范数据与先前报告一致。
本研究提供了亚洲成年人ET-ECochG的初步规范数据。ECochG各成分似乎不受种族或性别的影响。得出的规范数据可用于临床应用,并作为未来涉及亚洲人群研究的参考。