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病原体水平的量化对于比较对病原体暴露的反应是必要的：对戴维等人《另一种白鼻综合征转录组》的评论

Quantification of pathogen levels is necessary to compare responses to pathogen exposure: Comment on Davy et al. "The other white-nose syndrome transcriptome".

作者信息

Field Kenneth A

机构信息

Department of Biology Bucknell University Lewisburg Pennsylvania.

出版信息

Ecol Evol. 2018 May 8;8(11):5235-5237. doi: 10.1002/ece3.4034. eCollection 2018 Jun.

DOI:10.1002/ece3.4034
PMID:29938047
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6010789/
Abstract

When studying host responses to the presence of pathogens, the pathogen levels should be verified within the samples. The RNA-Seq samples from Davy et al. (2017) do not contain detectable pathogen levels compared to other studies. Future studies will be necessary to determine how hosts resistant to white-nose syndrome respond differently than susceptible hosts at the whole-transcriptome level. : https://doi.org/10.1002/ece3.4035.

摘要

在研究宿主对病原体存在的反应时，应在样本中验证病原体水平。与其他研究相比，来自戴维等人（2017年）的RNA测序样本中未检测到病原体水平。未来有必要开展研究，以确定对白鼻综合征具有抗性的宿主与易感宿主在全转录组水平上的反应有何不同。: https://doi.org/10.1002/ece3.4035

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本文引用的文献

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The other white-nose syndrome transcriptome: Tolerant and susceptible hosts respond differently to the pathogen .另一种白鼻综合征转录组：耐受宿主和易感宿主对病原体的反应不同
Ecol Evol. 2017 Aug 2;7(18):7161-7170. doi: 10.1002/ece3.3234. eCollection 2017 Sep.
2
Pseudogymnoascus destructans transcriptome changes during white-nose syndrome infections.拟茎点霉属（Pseudogymnoascus destructans）在白鼻综合征感染过程中的转录组变化。
Virulence. 2017 Nov 17;8(8):1695-1707. doi: 10.1080/21505594.2017.1342910. Epub 2017 Jul 13.
3
Energy conserving thermoregulatory patterns and lower disease severity in a bat resistant to the impacts of white-nose syndrome.对白鼻综合征影响具有抗性的蝙蝠的节能体温调节模式及较低的疾病严重程度
J Comp Physiol B. 2018 Jan;188(1):163-176. doi: 10.1007/s00360-017-1109-2. Epub 2017 Jun 8.
4
Near-optimal probabilistic RNA-seq quantification.近乎最优的概率 RNA-seq 定量。
Nat Biotechnol. 2016 May;34(5):525-7. doi: 10.1038/nbt.3519. Epub 2016 Apr 4.
5
White-nose syndrome survivors do not exhibit frequent arousals associated with Pseudogymnoascus destructans infection.白鼻综合征幸存者未表现出与毁灭隐球菌感染相关的频繁觉醒。
Front Zool. 2016 Mar 3;13:12. doi: 10.1186/s12983-016-0143-3. eCollection 2016.
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White-nose syndrome without borders: Pseudogymnoascus destructans infection tolerated in Europe and Palearctic Asia but not in North America.白鼻综合征无国界：欧洲和古北亚地区耐受毁灭假裸囊菌感染，但北美不然。
Sci Rep. 2016 Jan 29;6:19829. doi: 10.1038/srep19829.
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The White-Nose Syndrome Transcriptome: Activation of Anti-fungal Host Responses in Wing Tissue of Hibernating Little Brown Myotis.白鼻综合征转录组：冬眠的小棕蝠翼组织中抗真菌宿主反应的激活
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Nonlethal screening of bat-wing skin with the use of ultraviolet fluorescence to detect lesions indicative of white-nose syndrome.利用紫外线荧光对蝙蝠翅膀皮肤进行非致死性筛查，以检测表明白鼻综合征的病变。
J Wildl Dis. 2014 Jul;50(3):566-73. doi: 10.7589/2014-03-058. Epub 2014 May 22.
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