Faculty of Physical Education and Sport Sciences, Department of Exercise Physiology, University of Guilan, Rasht, Iran ; and.
Department of Exercise Physiology, Sport Sciences Research Institute, Tehran, Iran.
J Strength Cond Res. 2021 Mar 1;35(3):731-738. doi: 10.1519/JSC.0000000000002709.
Safarimosavi, S, Mohebbi, H, and Rohani, H. High-intensity interval vs. continuous endurance training: Preventive effects on hormonal changes and physiological adaptations in prediabetes patients. J Strength Cond Res 35(3): 731-738, 2021-The aim of this study was to examine the effects of a 12-week high-intensity interval training (HIIT) intervention, or an isocaloric continuous endurance training (CET) intervention on insulin resistance indices and change in irisin and preptin in patients with prediabetes. Thirty-two prediabetic male patients (age = 38.7 ± 4; body mass index = 26.9 ± 1.4 kg·m-2; and V̇o2peak = 2.49 ± 0.22 L·min-1) were randomly assigned into 3 training groups (N = 8). These groups were matched based on the required energy expenditure (EE) for completing each protocol: (a) HIIT (10 × 60 seconds at 90% peak oxygen uptake [V̇o2peak], 1: 1 work to recovery at 50 W), (b) CET at an intensity equivalent to maximal fat oxidation (Fatmax) (CETFAT) (pedaling for a duration that expends an equivalent EE to an HIIT session [E ≈ HIIT]), (c) CET at an intensity equivalent to anaerobic threshold (CETAT) (E ≈ HIIT), and (d) the control group (CON): continued to perform their daily activities. After intervention, blood glucose levels were significantly (p < 0.05) lower in the HIIT group compared with CETAT group. Exercise training improved the insulin resistance index by 35, 28, and 37% in CETFAT, CETAT, and HIIT groups, respectively. Irisin concentrations in the HIIT and CETAT groups was significantly (p < 0.05) decreased compared with the pre-training values. Also, HIIT and CETFAT resulted in significant (p < 0.05) changes in preptin concentration compared with baseline. This study demonstrated that both HIIT and CETFAT protocols had similar effects on the insulin resistance index of prediabetic patients. Also, the intensity and type of exercise were effective factors in changing irisin and preptin concentrations.
萨法里莫萨维、S、莫赫比、H 和罗哈尼、H. 高强度间歇训练与持续耐力训练：对糖尿病前期患者激素变化和生理适应的预防作用。J 力量与体能研究 35(3)：731-738，2021-本研究旨在探讨 12 周高强度间歇训练（HIIT）干预或等热量持续耐力训练（CET）干预对糖尿病前期患者胰岛素抵抗指数和鸢尾素和前肽变化的影响。32 名糖尿病前期男性患者（年龄=38.7±4；体重指数=26.9±1.4kg·m-2；峰值摄氧量=2.49±0.22L·min-1）被随机分为 3 个训练组（N=8）。这些组是根据完成每个方案所需的能量消耗（EE）进行匹配的：（a）HIIT（10×60 秒，90%峰值摄氧量[V̇o2peak]，1:1 工作与恢复至 50W），（b）CET 在最大脂肪氧化强度等效（Fatmax）（CETFAT）（蹬踏持续时间消耗与 HIIT 会话等效的 EE[E≈HIIT]），（c）CET 在无氧阈强度等效（CETAT）（E≈HIIT），和（d）对照组（CON）：继续进行日常活动。干预后，与 CETAT 组相比，HIIT 组的血糖水平显著（p<0.05）降低。运动训练使 CETFAT、CETAT 和 HIIT 组的胰岛素抵抗指数分别提高了 35%、28%和 37%。HIIT 和 CETAT 组的鸢尾素浓度与训练前相比显著（p<0.05）降低。此外，HIIT 和 CETFAT 导致前肽浓度与基线相比显著（p<0.05）变化。本研究表明，HIIT 和 CETFAT 方案对糖尿病前期患者的胰岛素抵抗指数均有相似的影响。此外，运动强度和类型是影响鸢尾素和前肽浓度变化的有效因素。
