Henan Province People's Hospital, Henan University, Zhengzhou, China.
Adv Exp Med Biol. 2018;1068:1-6. doi: 10.1007/978-981-13-0502-3_1.
The single-cell as the basic unit of biological organs and tissues has recently been considered an important window to furthermore understand molecular mechanisms of organ function and biology. The current issue with a special focus on single cell biomedicine is the first effort to collect the evidence of disease-associated single cell research, define the significance of single cell biomedicine in the pathogenesis of diseases, value the correlation of single cell gene sequencing with disease-specific biomarkers, and monitor the dynamics of RNA processes and responses to microenvironmental changes and drug resistances.
单细胞作为生物器官和组织的基本单位，最近被认为是进一步了解器官功能和生物学分子机制的重要窗口。本期特别关注单细胞生物医学，首次努力收集与疾病相关的单细胞研究证据，定义单细胞生物医学在疾病发病机制中的意义，重视单细胞基因测序与疾病特异性生物标志物的相关性，并监测 RNA 过程的动态以及对微环境变化和耐药性的反应。
