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南非夸祖鲁-纳塔尔省伊泰夸尼地区孕妇的抗逆转录病毒治疗起始情况及产前护理预约做法

Antiretroviral initiation of pregnant women and antenatal care booking practices in eThekwini District, KwaZulu-Natal, South Africa.

作者信息

Nozulu Nomonde, Gaede Bernard M

机构信息

Department of Family Medicine, School of Nursing and Public Health, University of KwaZulu-Natal.

出版信息

Afr J Prim Health Care Fam Med. 2018 May 24;10(1):e1-e9. doi: 10.4102/phcfm.v10i1.1606.

DOI:10.4102/phcfm.v10i1.1606
PMID:29943591
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6018727/
Abstract

BACKGROUND

The introduction of antiretroviral therapy (ART) in South Africa began as part of the prevention of mother-to-child transmission programme. For significant reduction of vertical transmission, early antenatal care booking and ART initiation are necessary.

AIM

This study aimed to evaluate ART initiation and booking practices of women attending antenatal care in eThekwini district during financial years (FY) 2010/2011 and 2013/2014.

METHODS

An observational study used a retrospective chart review at four eThekwini district community health centres (CHC). From these CHCs, records of women that initiated ART in FY10/11 and FY13/14 were reviewed and compared for ART initiation delays and booking practices.

RESULTS

A total of 2749 pregnant women who attended antenatal care (ANC) at the study sites were found eligible for ART; of these, 49% (n = 1334) attended ANC in FY10/11 while 51% (n = 1414) attended in FY13/14. In FY10/11, 46% (n = 610) and 60 % (n = 855) of the womenwere initiated on ART during pregnancy. The mean gestational age at booking for FY10/11 was 20.88 (standard deviation [s.d.] = 5.6) and 18.40 (s.d. = 6.2) in FY13/14. The mean gestational age at ART initiation for women who initiated ART in FY10/11 was 26.30 (s.d. = 6.02) and in FY13/14 it was 19.06 (s.d. = 6.86).

CONCLUSION

In FY13/14 ART initiations occurred within 4 days after booking. ANC booking before 20 weeks was found to have improved between the two years from 39% to 58%;however, on average, in both years women booked during the second trimester.

摘要

背景

抗逆转录病毒疗法(ART)在南非的引入始于预防母婴传播项目。为了大幅降低垂直传播率,早期产前检查预约和启动抗逆转录病毒疗法是必要的。

目的

本研究旨在评估2010/2011财政年度和2013/2014财政年度在伊特夸尼地区接受产前检查的妇女的抗逆转录病毒疗法启动情况和预约做法。

方法

一项观察性研究采用回顾性图表审查,在伊特夸尼地区的四个社区卫生中心(CHC)进行。从这些社区卫生中心,对2010/11财政年度和2013/14财政年度启动抗逆转录病毒疗法的妇女记录进行审查,并比较抗逆转录病毒疗法启动延迟情况和预约做法。

结果

在研究地点接受产前检查(ANC)的2749名孕妇被认定符合接受抗逆转录病毒疗法的条件;其中,49%(n = 1334)在2010/11财政年度接受产前检查,而51%(n = 1414)在2013/14财政年度接受产前检查。在2010/11财政年度,46%(n = 610)和60%(n = 855)的妇女在孕期开始接受抗逆转录病毒疗法。2010/11财政年度的平均预约孕周为20.88(标准差[s.d.] = 5.6),2013/14财政年度为18.40(s.d. = 6.2)。2010/11财政年度开始接受抗逆转录病毒疗法的妇女开始治疗时的平均孕周为26.30(s.d. = 6.02),2013/14财政年度为19.06(s.d. = 6.86)。

结论

在2013/14财政年度,抗逆转录病毒疗法在预约后4天内启动。发现两年间20周前的产前检查预约情况有所改善,从39%提高到58%;然而,平均而言,两年中妇女都是在孕中期进行预约。

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