Suppr超能文献

[巨细胞病毒在婴儿期耳聋及不明原因耳聋中的作用]

[The role of cytomegalovirus in infantile deafness and deafness of unknown origin].

作者信息

Desnos J, Carbonnelle B, Kouyoumdjian S, Beucher A, Vacher S

出版信息

Ann Otolaryngol Chir Cervicofac. 1985;102(5):351-6.

PMID:2994539
Abstract

It is widely accepted that the cause of congenital deafness is genetic in one third of cases roughly, is due to acquired affections during pregnancy or delivery in another third and remains unknown in the last third. It is possible that the cytomegalovirus (CMV) plays an important role in the latter group. The CMV is thought to be involved in 10 to 30% of cases of auditory sequelae from fetal infection, either severe neonatal CMV-induced disease, which is rare, or the frequent subclinical infections affecting an average of 1% of newborn infants. The only certain way to determine the importance of the role of CMV in deafness of unknown etiology is large-scale neonatal biologic screening followed by long-term audiologic surveillance: currently available documented data suggest that this role is very important.

摘要

普遍认为,先天性耳聋的病因大致有三分之一是遗传因素,另外三分之一是由孕期或分娩期间获得性疾病引起的,而最后三分之一的病因仍不明确。巨细胞病毒(CMV)在后一组病因中可能起着重要作用。据认为,在胎儿感染导致的听觉后遗症病例中,10%至30%与CMV有关,这些病例要么是罕见的严重新生儿CMV诱发疾病,要么是平均影响1%新生儿的常见亚临床感染。确定CMV在病因不明的耳聋中所起作用的重要性的唯一确定方法是进行大规模新生儿生物学筛查,然后进行长期听力监测:目前可得的文献数据表明,这一作用非常重要。

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验