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[腰椎间盘突出症破裂预后预测因素的逻辑回归分析]

[Logistic regression analysis on the outcome predictive factors of ruptured lumbar disc herniation].

作者信息

Yu Peng-Fei, Liu Jin-Tao, Ma Zhi-Jia, Zhong Ming, Li Xiao-Chun, Jiang Hong

机构信息

Suzhou Traditional Chinese Medicine Hospital Affiliated to Nanjing University of Traditional Chinese Medicine, Suzhou 215009, Jiangsu, China;

出版信息

Zhongguo Gu Shang. 2018 Jun 25;31(6):522-527. doi: 10.3969/j.issn.1003-0034.2018.06.008.

Abstract

OBJECTIVE

To investigate the outcome predictive factors of ruptured lumbar disc herniation after conservative treatment.

METHODS

From June 2009 to June 2016, 147 patients with ruptured lumbar intervertebral disc herniation were treated with conservative treatment in the orthopedics department of Suzhou Traditional Chinese Medicine Hospital for clinical efficacy and MRI follow-up. Multivariate Logistic regression analysis(Stepwise regression method)was used to analyze the relationship between the 11 categorical variables and absorptivity of protrusions: sex(X1), age(X2), course of disease(X3) , the rate of protrusion(X4), the Komori type(X5), the MSU type(X6), the Iwabuchi type(X7), the Pfirrmann grade(X8), the Modic change on adjacent vertebrae(X9), spinal canal morphology(X10), the Schizas types of cauda equina sedimentation sign(X11).

RESULTS

A total of 64 cases of prominent reabsorption among all cases followed-up (absorption rate>=30%), accounting for 43.5%. The reabsorption of protrusions is more likely to occur in patients with a duration of less than 1 year(0.006), MSU type 3 (0.001), Iwabuchi type 1 or 5 (0.000), the Schizas type of cauda equina sedimentation sign A or B(0.004). Regression equation Y=-10.363+1.916X3+1.446X4-1.445X5+2.070X6+4.679X7+1.125X9+1.023X10+2.223X11. Such factors as age, gender, Pfirrmann classification and spinal canal morphology had no significant effect on reabsorption of protrusions.

CONCLUSIONS

Ruptured lumbar disc herniation can be reabsorbed after nonoperative treatment. And the reabsorption of protrusions is more likely to occur in patients with a duration of less than 1 year, MSU type 3, Iwabuchi type 1 or 5, the Schizas type of cauda equina sedimentation sign A or B, which can be used as the key reference factors for predicting the outcome of the projections.

摘要

目的

探讨破裂型腰椎间盘突出症保守治疗后的疗效预测因素。

方法

选取2009年6月至2016年6月在苏州市中医医院骨科接受保守治疗的147例破裂型腰椎间盘突出症患者,进行临床疗效及MRI随访。采用多因素Logistic回归分析(逐步回归法)分析11个分类变量与突出物吸收率的关系:性别(X1)、年龄(X2)、病程(X3)、突出率(X4)、小森分型(X5)、MSU分型(X6)、岩渊分型(X7)、Pfirrmann分级(X8)、相邻椎体Modic改变(X9)、椎管形态(X10)、马尾沉降征Schizas分型(X11)。

结果

随访的所有病例中共有64例突出物吸收(吸收率>=30%),占43.5%。突出物吸收更易发生在病程小于1年(0.006)、MSU 3型(0.001)、岩渊1型或5型(0.000)、马尾沉降征Schizas A或B型(0.004)的患者中。回归方程Y=-10.363+1.916X3+1.446X4-1.445X5+2.070X6+4.679X7+1.125X9+1.023X10+2.223X11。年龄、性别、Pfirrmann分级及椎管形态等因素对突出物吸收无显著影响。

结论

破裂型腰椎间盘突出症经非手术治疗后可发生吸收。突出物吸收更易发生在病程小于1年、MSU 3型、岩渊1型或5型、马尾沉降征Schizas A或B型的患者中,可作为预测突出物转归的关键参考因素。

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