肺移植受者旅行距离与移植后生存率之间的关联。
The Association Between Lung Recipient Travel Distance and Posttransplant Survival.
作者信息
Tsuang Wayne M, Lin Songhua, Valapour Maryam, Udeh Belinda L, Budev Marie, Schold Jesse D
机构信息
1 Department of Pulmonary Medicine, Respiratory Institute, Cleveland Clinic, Cleveland, Ohio.
2 Department of Quantitative Health Sciences, Cleveland Clinic, Cleveland, Ohio.
出版信息
Prog Transplant. 2018 Sep;28(3):231-235. doi: 10.1177/1526924818781570. Epub 2018 Jun 26.
INTRODUCTION
Recipient travel distance may be an unrecognized burden in lung transplantation.
DESIGN
Retrospective single-center cohort study of all adult (≥18 years) first-time lung-only transplants from January 1, 2010, until February 28, 2017. Recipient distance to transplant center was calculated using the linear distance from the recipient's home zip code to the Cleveland Clinic in Cleveland, Ohio.
RESULTS
569 recipients met inclusion criteria. Posttransplant graft survival was 85%, 88%, 91%, and 91% at 1 year and 49%, 52%, 57%, and 56% at 5 years posttransplant for recipient travel distances of ≤50, >50 to ≤250, >250 to ≤500, and >500 miles, respectively ( P = .10).
DISCUSSION
We found no significant relationship between recipient travel distance and posttransplant graft survival. In carefully selected recipients, travel distance is not a significant barrier to successful posttransplant outcomes which may be important for patient decision-making and donor allocation policy. These data should be validated in a national cohort.
引言
受者的行程距离可能是肺移植中一个未被认识到的负担。
设计
对2010年1月1日至2017年2月28日期间所有成年（≥18岁）首次单纯肺移植进行回顾性单中心队列研究。使用从受者家庭邮政编码到俄亥俄州克利夫兰市克利夫兰诊所的直线距离计算受者到移植中心的距离。
结果
569名受者符合纳入标准。移植后1年时，行程距离≤50英里、>50至≤250英里、>250至≤500英里和>500英里的受者移植后移植物存活率分别为85%、88%、91%和91%；移植后5年时分别为49%、52%、57%和56%（P = 0.10）。
讨论
我们发现受者行程距离与移植后移植物存活率之间无显著关系。在经过精心挑选的受者中，行程距离并非移植后成功结局的重大障碍，这对于患者决策和供体分配政策可能很重要。这些数据应在全国队列中进行验证。
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